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RASSF1 tumor suppressor gene in pancreatic ductal adenocarcinoma: correlation of expression, chromosomal status and epigenetic changes

BACKGROUND: The Ras Association Domain Family Member 1 (RASSF1) is one of the most frequently reported methylation-inactivated tumor suppressor genes in primary pancreatic ductal adenocarcinomas (PDAC). Limited information is still available about the impact of RASSF1 gene silencing on the expressio...

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Detalles Bibliográficos
Autores principales:	Amato, Eliana, Barbi, Stefano, Fassan, Matteo, Luchini, Claudio, Vicentini, Caterina, Brunelli, Matteo, Malleo, Giuseppe, Scarpa, Aldo, Malpeli, Giorgio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710004/ https://www.ncbi.nlm.nih.gov/pubmed/26754001 http://dx.doi.org/10.1186/s12885-016-2048-0

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