Exosomes derived from atorvastatin-modified bone marrow dendritic cells ameliorate experimental autoimmune myasthenia gravis by up-regulated levels of IDO/Treg and partly dependent on FasL/Fas pathway

BACKGROUND: Previously, we have demonstrated that spleen-derived dendritic cells (DCs) modified with atorvastatin suppressed immune responses of experimental autoimmune myasthenia gravis (EAMG). However, the effects of exosomes derived from atorvastatin-modified bone marrow DCs (BMDCs) (statin-Dex)...

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Detalles Bibliográficos
Autores principales: Li, Xiao-Li, Li, Heng, Zhang, Min, Xu, Hua, Yue, Long-Tao, Zhang, Xin-Xin, Wang, Shan, Wang, Cong-Cong, Li, Yan-Bin, Dou, Ying-Chun, Duan, Rui-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710023/
https://www.ncbi.nlm.nih.gov/pubmed/26757900
http://dx.doi.org/10.1186/s12974-016-0475-0

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