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pATsi: Paralogs and Singleton Genes from Arabidopsis thaliana

Arabidopsis thaliana is widely accepted as a model species in plant biology. Its genome, due to its small size and diploidy, was the first to be sequenced among plants, making this species also a reference for plant comparative genomics. Nevertheless, the evolutionary mechanisms that shaped the Arab...

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Autores principales: Ambrosino, Luca, Bostan, Hamed, di Salle, Pasquale, Sangiovanni, Mara, Vigilante, Alessandra, Chiusano, Maria L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710182/
https://www.ncbi.nlm.nih.gov/pubmed/26792975
http://dx.doi.org/10.4137/EBO.S32536
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author Ambrosino, Luca
Bostan, Hamed
di Salle, Pasquale
Sangiovanni, Mara
Vigilante, Alessandra
Chiusano, Maria L.
author_facet Ambrosino, Luca
Bostan, Hamed
di Salle, Pasquale
Sangiovanni, Mara
Vigilante, Alessandra
Chiusano, Maria L.
author_sort Ambrosino, Luca
collection PubMed
description Arabidopsis thaliana is widely accepted as a model species in plant biology. Its genome, due to its small size and diploidy, was the first to be sequenced among plants, making this species also a reference for plant comparative genomics. Nevertheless, the evolutionary mechanisms that shaped the Arabidopsis genome are still controversial. Indeed, duplications, translocations, inversions, and gene loss events that contributed to the current organization are difficult to be traced. A reliable identification of paralogs and single-copy genes is essential to understand these mechanisms. Therefore, we implemented a dedicated pipeline to identify paralog genes and classify single-copy genes into opportune categories. PATsi, a web-accessible database, was organized to allow the straightforward access to the paralogs organized into networks and to the classification of single-copy genes. This permits to efficiently explore the gene collection of Arabidopsis for evolutionary investigations and comparative genomics.
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spelling pubmed-47101822016-01-20 pATsi: Paralogs and Singleton Genes from Arabidopsis thaliana Ambrosino, Luca Bostan, Hamed di Salle, Pasquale Sangiovanni, Mara Vigilante, Alessandra Chiusano, Maria L. Evol Bioinform Online Software or Database Review Arabidopsis thaliana is widely accepted as a model species in plant biology. Its genome, due to its small size and diploidy, was the first to be sequenced among plants, making this species also a reference for plant comparative genomics. Nevertheless, the evolutionary mechanisms that shaped the Arabidopsis genome are still controversial. Indeed, duplications, translocations, inversions, and gene loss events that contributed to the current organization are difficult to be traced. A reliable identification of paralogs and single-copy genes is essential to understand these mechanisms. Therefore, we implemented a dedicated pipeline to identify paralog genes and classify single-copy genes into opportune categories. PATsi, a web-accessible database, was organized to allow the straightforward access to the paralogs organized into networks and to the classification of single-copy genes. This permits to efficiently explore the gene collection of Arabidopsis for evolutionary investigations and comparative genomics. Libertas Academica 2016-01-11 /pmc/articles/PMC4710182/ /pubmed/26792975 http://dx.doi.org/10.4137/EBO.S32536 Text en © 2016 the author(s), publisher and licensee Libertas Academica Ltd. This is an open-access article distributed under the terms of the Creative Commons CC-BY-NC 3.0 License.
spellingShingle Software or Database Review
Ambrosino, Luca
Bostan, Hamed
di Salle, Pasquale
Sangiovanni, Mara
Vigilante, Alessandra
Chiusano, Maria L.
pATsi: Paralogs and Singleton Genes from Arabidopsis thaliana
title pATsi: Paralogs and Singleton Genes from Arabidopsis thaliana
title_full pATsi: Paralogs and Singleton Genes from Arabidopsis thaliana
title_fullStr pATsi: Paralogs and Singleton Genes from Arabidopsis thaliana
title_full_unstemmed pATsi: Paralogs and Singleton Genes from Arabidopsis thaliana
title_short pATsi: Paralogs and Singleton Genes from Arabidopsis thaliana
title_sort patsi: paralogs and singleton genes from arabidopsis thaliana
topic Software or Database Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710182/
https://www.ncbi.nlm.nih.gov/pubmed/26792975
http://dx.doi.org/10.4137/EBO.S32536
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