Migratory CD103(+) dendritic cells suppress helminth-driven type 2 immunity through constitutive expression of IL-12

CD8α(+) and CD103(+) dendritic cells (DCs) play a central role in the development of type 1 immune responses. However, their role in type 2 immunity remains unclear. We examined this issue using Batf3(−/−) mice, in which both of these DC subsets are missing. We found that Th2 cell responses, and rel...

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Detalles Bibliográficos
Autores principales: Everts, Bart, Tussiwand, Roxane, Dreesen, Leentje, Fairfax, Keke C., Huang, Stanley Ching-Cheng, Smith, Amber M., O’Neill, Christina M., Lam, Wing Y., Edelson, Brian T., Urban, Joseph F., Murphy, Kenneth M., Pearce, Edward J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710198/
https://www.ncbi.nlm.nih.gov/pubmed/26712805
http://dx.doi.org/10.1084/jem.20150235

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