Microenvironment rigidity modulates responses to the HER2 receptor tyrosine kinase inhibitor lapatinib via YAP and TAZ transcription factors

Stiffness is a biophysical property of the extracellular matrix that modulates cellular functions, including proliferation, invasion, and differentiation, and it also may affect therapeutic responses. Therapeutic durability in cancer treatments remains a problem for both chemotherapies and pathway-t...

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Detalles Bibliográficos
Autores principales: Lin, Chun-Han, Pelissier, Fanny A., Zhang, Hui, Lakins, Jon, Weaver, Valerie M., Park, Catherine, LaBarge, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710228/
https://www.ncbi.nlm.nih.gov/pubmed/26337386
http://dx.doi.org/10.1091/mbc.E15-07-0456

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710228/
https://www.ncbi.nlm.nih.gov/pubmed/26337386
http://dx.doi.org/10.1091/mbc.E15-07-0456

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