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Basic mechanism for biorientation of mitotic chromosomes is provided by the kinetochore geometry and indiscriminate turnover of kinetochore microtubules

Accuracy of chromosome segregation relies on the ill-understood ability of mitotic kinetochores to biorient, whereupon each sister kinetochore forms microtubule (MT) attachments to only one spindle pole. Because initial MT attachments result from chance encounters with the kinetochores, biorientatio...

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Detalles Bibliográficos
Autores principales:	Zaytsev, Anatoly V., Grishchuk, Ekaterina L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710231/ https://www.ncbi.nlm.nih.gov/pubmed/26424798 http://dx.doi.org/10.1091/mbc.E15-06-0384

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