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Apolar and polar transitions drive the conversion between amoeboid and mesenchymal shapes in melanoma cells

Melanoma cells can adopt two functionally distinct forms, amoeboid and mesenchymal, which facilitates their ability to invade and colonize diverse environments during the metastatic process. Using quantitative imaging of single living tumor cells invading three-dimensional collagen matrices, in tand...

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Detalles Bibliográficos
Autores principales: Cooper, Sam, Sadok, Amine, Bousgouni, Vicky, Bakal, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710245/
https://www.ncbi.nlm.nih.gov/pubmed/26310441
http://dx.doi.org/10.1091/mbc.E15-06-0382