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Insulin-Producing Cells Differentiated from Human Bone Marrow Mesenchymal Stem Cells In Vitro Ameliorate Streptozotocin-Induced Diabetic Hyperglycemia
BACKGROUND: The two major obstacles in the successful transplantation of islets for diabetes treatment are inadequate supply of insulin-producing tissue and immune rejection. Induction of the differentiation of human bone marrow-derived mesenchymal stem cells (hMSCs) into insulin-producing cells (IP...
Autores principales: | Xin, Ying, Jiang, Xin, Wang, Yishu, Su, Xuejin, Sun, Meiyu, Zhang, Lihong, Tan, Yi, Wintergerst, Kupper A., Li, Yan, Li, Yulin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710504/ https://www.ncbi.nlm.nih.gov/pubmed/26756576 http://dx.doi.org/10.1371/journal.pone.0145838 |
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