Increased mitochondrial ATP production capacity in brain of healthy mice and a mouse model of isolated complex I deficiency after isoflurane anesthesia

We reported before that the minimal alveolar concentration (MAC) of isoflurane is decreased in complex I-deficient mice lacking the NDUFS4 subunit of the respiratory chain (RC) (1.55 and 0.81 % at postnatal (PN) 22–25 days and 1.68 and 0.65 % at PN 31–34 days for wildtype (WT) and CI-deficient KO, r...

Descripción completa

Detalles Bibliográficos
Autores principales: Manjeri, Ganesh R., Rodenburg, Richard J., Blanchet, Lionel, Roelofs, Suzanne, Nijtmans, Leo G., Smeitink, Jan A., Driessen, Jacques J., Koopman, Werner J. H., Willems, Peter H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710641/
https://www.ncbi.nlm.nih.gov/pubmed/26310962
http://dx.doi.org/10.1007/s10545-015-9885-x

Ejemplares similares

Ejemplares similares