Cargando…

The 5-HT(2C) receptor agonist, lorcaserin, and the 5-HT(6) receptor antagonist, SB-742457, promote satiety; a microstructural analysis of feeding behaviour

RATIONALE: Whilst the FDA-approved anorectic, lorcaserin and various 5-hydroxytryptamine (5-HT)(6) receptor antagonists reduce feeding, a direct assessment of their impact upon feeding behaviour is less clear. We therefore examined the action of lorcaserin and the clinical-stage developmental candid...

Descripción completa

Detalles Bibliográficos
Autores principales:	Higgs, Suzanne, Cooper, Alison J., Barnes, Nicholas M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2015
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710672/ https://www.ncbi.nlm.nih.gov/pubmed/26507195 http://dx.doi.org/10.1007/s00213-015-4112-x

Ejemplares similares

Characterization of the 5-HT(2C) receptor agonist lorcaserin on efficacy and safety measures in a rat model of diet-induced obesity
por: Higgins, Guy A, et al.
Publicado: (2015)

5-HT1A agonists, 5-HT3 antagonists and benzodiazepines : their comparative behavioural pharmacology /
Publicado: (1991)

CGRP Receptor Antagonists and 5-HT1F Receptor Agonist in the Treatment of Migraine
por: Capi, Matilde, et al.
Publicado: (2021)

Agonists and antagonists induce different palonosetron dissociation rates in 5-HT(3)A and 5-HT(3)AB receptors()
por: Lummis, Sarah C.R., et al.
Publicado: (2013)

The 5-HT(7) receptor antagonist SB 269970 ameliorates corticosterone-induced alterations in 5-HT(7) receptor-mediated modulation of GABAergic transmission in the rat dorsal raphe nucleus
por: Sowa, Joanna, et al.
Publicado: (2018)

Azologization of serotonin 5-HT(3) receptor antagonists
por: Rustler, Karin, et al.
Publicado: (2019)

Inhibition of Cocaine and 3,4-Methylenedioxypyrovalerone (MDPV) Self-Administration by Lorcaserin Is Mediated by 5-HT2C Receptors in Rats
por: Gannon, Brenda M., et al.
Publicado: (2018)

Constitutively Active 5-HT Receptors: An Explanation of How 5-HT Antagonists Inhibit Gut Motility in Species Where 5-HT is Not an Enteric Neurotransmitter?
por: Spencer, Nick J.
Publicado: (2015)

Existence of Brain 5-HT1A–5-HT2A Isoreceptor Complexes with Antagonistic Allosteric Receptor–Receptor Interactions Regulating 5-HT1A Receptor Recognition
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2017)

Co-administration of 5-HT6 receptor antagonists with clozapine, risperidone, and a 5-HT2A receptor antagonist: effects on prepulse inhibition in rats
por: Fijał, Katarzyna, et al.
Publicado: (2013)

Effect of Selective 5-HT6R Agonist on Expression of 5-HT Receptor and Neurotransmitter in Vascular Dementia Rats
por: Yu, Haining, et al.
Publicado: (2017)

Distribution of 5-HT(3), 5-HT(4), and 5-HT(7) Receptors Along the Human Colon
por: Yaakob, Nor S, et al.
Publicado: (2015)

The muscarinic antagonists scopolamine and atropine are competitive antagonists at 5-HT(3) receptors
por: Lochner, Martin, et al.
Publicado: (2016)

Anti-PTSD Effects of Hypidone Hydrochloride (YL-0919): A Novel Combined Selective 5-HT Reuptake Inhibitor/5-HT(1A) Receptor Partial Agonist/5-HT(6) Receptor Full Agonist
por: Liu, Wen-Gang, et al.
Publicado: (2021)

5-HT(3) Receptors
por: Lummis, Sarah C. R.
Publicado: (2012)

Two randomized controlled trials of SB742457 in mild-to-moderate Alzheimer's disease
por: Maher-Edwards, Gareth, et al.
Publicado: (2015)

Cardiac Roles of Serotonin (5-HT) and 5-HT-Receptors in Health and Disease
por: Neumann, Joachim, et al.
Publicado: (2023)

A single channel mutation alters agonist efficacy at 5-HT(3)A and 5-HT(3)AB receptors
por: Thompson, A J, et al.
Publicado: (2013)

Role of 5-HT(2A) receptor antagonists in the treatment of insomnia
por: Vanover, Kimberly E, et al.
Publicado: (2010)

Effects of 5‐HT(₃) receptor antagonists on cisplatin‐induced kidney injury
por: Goda, Mitsuhiro, et al.
Publicado: (2021)

Dibenzofuranylethylamines as 5-HT(2A/2C) Receptor Agonists
por: Yempala, Thirumal, et al.
Publicado: (2020)

Translating the promise of 5HT(4) receptor agonists for the treatment of depression
por: Murphy, Susannah E, et al.
Publicado: (2021)

Effects of the Selective 5-HT7 Receptor Antagonist SB-269970 and Amisulpride on Ketamine-Induced Schizophrenia-like Deficits in Rats
por: Nikiforuk, Agnieszka, et al.
Publicado: (2013)

Review: 5-HT(1), 5-HT(2), 5-HT(3) and 5-HT(7) Receptors and their Role in the Modulation of Pain Response in the Central Nervous System
por: Cortes-Altamirano, Jose Luis, et al.
Publicado: (2018)

Human 5–HT(4) and 5–HT(7) Receptor Splice Variants: Are they Important?
por: Coupar, Ian M, et al.
Publicado: (2007)

Discriminating between 5-HT(3)A and 5-HT(3)AB receptors
por: Thompson, AJ, et al.
Publicado: (2013)

Conservation of 5-HT(1A) receptor-mediated autoinhibition of serotonin (5-HT) neurons in mice with altered 5-HT homeostasis
por: Araragi, Naozumi, et al.
Publicado: (2013)

The role of 5-HT receptors in depression
por: Yohn, Christine N., et al.
Publicado: (2017)

5-HT Receptors and Temperature Homeostasis
por: Voronova, Irina P.
Publicado: (2021)

Reduction of the serotonin 5-HT(1B) and 5-HT(2A) receptor-mediated contraction of human pulmonary artery by the combined 5-HT(1B) receptor antagonist and serotonin transporter inhibitor LY393558
por: Baranowska-Kuczko, Marta, et al.
Publicado: (2020)

Distribution of cells responsive to 5-HT(6) receptor antagonist-induced hypophagia
por: Garfield, Alastair S., et al.
Publicado: (2014)

Recent advances in antiemetics: new formulations of 5HT(3)-receptor antagonists
por: Gilmore, James, et al.
Publicado: (2018)

Serotonin 5-HT3 Receptor Antagonist for Treatment of Severe Diabetic Diarrhea
por: Murao, Satoshi, et al.
Publicado: (2010)

Dual 5-HT(3) and 5-HT(6) Receptor Antagonist FPPQ Normalizes Phencyclidine-Induced Disruption of Brain Oscillatory Activity in Rats
por: Castañé, Anna, et al.
Publicado: (2022)

Maternal feeding patterns affect the offspring’s brain: focus on serotonin 5-HT(2C) and 5-HT(2A) receptors
por: Gawlińska, Kinga, et al.
Publicado: (2021)

Enhancement by Hydrogen Peroxide of Calcium Signals in Endothelial Cells Induced by 5-HT1B and 5-HT2B Receptor Agonists
por: Avdonin, Pavel V., et al.
Publicado: (2019)

Altered 5-HT(2C )receptor agonist-induced responses and 5-HT(2C )receptor RNA editing in the amygdala of serotonin transporter knockout mice
por: Moya, Pablo R, et al.
Publicado: (2011)

5-HT3 and 5-HT4 antagonists inhibit peristaltic contractions in guinea-pig distal colon by mechanisms independent of endogenous 5-HT
por: Sia, Tiong C., et al.
Publicado: (2013)

Structure-Based Design and Optimization of FPPQ, a Dual-Acting 5-HT(3) and 5-HT(6) Receptor Antagonist with Antipsychotic and Procognitive Properties
por: Zajdel, Paweł, et al.
Publicado: (2021)

Characterization of Behavioral, Signaling and Cytokine Alterations in a Rat Neurodevelopmental Model for Schizophrenia, and Their Reversal by the 5-HT(6) Receptor Antagonist SB-399885
por: Shortall, Sinead E., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_2dm6r4890lacsbrjjqp4up7enb