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Neonatal mitochondrial abnormalities due to PINK1 deficiency: Proteomics reveals early changes relevant to Parkinson׳s disease

Parkinson׳s disease (PD), the second most common neurodegenerative disorder, affects roughly 7–10 million people worldwide. A wide array of research has suggested that PD has a mitochondrial component and that mitochondrial dysfunction occurs well in advance of the clinical manifestation of the dise...

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Detalles Bibliográficos
Autores principales: Villeneuve, Lance M., Purnell, Phillip R., Stauch, Kelly L., Fox, Howard S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710791/
https://www.ncbi.nlm.nih.gov/pubmed/26866053
http://dx.doi.org/10.1016/j.dib.2015.11.070