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Fatty acid nitroalkenes induce resistance to ischemic cardiac injury by modulating mitochondrial respiration at complex II
Nitro-fatty acids (NO(2)-FA) are metabolic and inflammatory-derived electrophiles that mediate pleiotropic signaling actions. It was hypothesized that NO(2)-FA would impact mitochondrial redox reactions to induce tissue-protective metabolic shifts in cells. Nitro-oleic acid (OA-NO(2)) reversibly inh...
Autores principales: | Koenitzer, Jeffrey R., Bonacci, Gustavo, Woodcock, Steven R., Chen, Chen-Shan, Cantu-Medellin, Nadiezhda, Kelley, Eric E., Schopfer, Francisco J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710799/ https://www.ncbi.nlm.nih.gov/pubmed/26722838 http://dx.doi.org/10.1016/j.redox.2015.11.002 |
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