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Trehalose-Based Block Copolycations Promote Polyplex Stabilization for Lyophilization and in Vivo pDNA Delivery

[Image: see text] The development and thorough characterization of nonviral delivery agents for nucleic acid and genome editing therapies are of high interest to the field of nanomedicine. Indeed, this vehicle class offers the ability to tune chemical architecture/biological activity and readily pac...

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Detalles Bibliográficos
Autores principales:	Tolstyka, Zachary P., Phillips, Haley, Cortez, Mallory, Wu, Yaoying, Ingle, Nilesh, Bell, Jason B., Hackett, Perry B., Reineke, Theresa M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2015
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710891/ https://www.ncbi.nlm.nih.gov/pubmed/26807438 http://dx.doi.org/10.1021/acsbiomaterials.5b00312

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