Polyarteritis Nodosa Presenting as Digital Gangrene and Breast Lesion following Exposure to Silicone Breast Implants

Polyarteritis nodosa (PAN) is a rare systemic necrotizing vasculitis of small and medium sized arteries. We report a case of a 49-year old woman who presented with PAN following exposure to silicone breast implants. Although the relationship between silicone implants and connective tissue diseases h...

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Detalles Bibliográficos
Autores principales: Homsi, Yamen, Carlson, John Andrew, Homsi, Samer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710902/
https://www.ncbi.nlm.nih.gov/pubmed/26844000
http://dx.doi.org/10.1155/2015/765170
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author Homsi, Yamen
Carlson, John Andrew
Homsi, Samer
author_facet Homsi, Yamen
Carlson, John Andrew
Homsi, Samer
author_sort Homsi, Yamen
collection PubMed
description Polyarteritis nodosa (PAN) is a rare systemic necrotizing vasculitis of small and medium sized arteries. We report a case of a 49-year old woman who presented with PAN following exposure to silicone breast implants. Although the relationship between silicone implants and connective tissue diseases has been investigated in the literature, no prior reports were found documenting PAN after silicone mammoplasty. While the pathogenesis of idiopathic PAN is not known yet, responsiveness to immunosuppressive therapy may suggest an immunologic mechanism. More robust research is needed to understand the connection between silicone breast implants and autoimmunity.
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spelling pubmed-47109022016-02-03 Polyarteritis Nodosa Presenting as Digital Gangrene and Breast Lesion following Exposure to Silicone Breast Implants Homsi, Yamen Carlson, John Andrew Homsi, Samer Case Rep Rheumatol Case Report Polyarteritis nodosa (PAN) is a rare systemic necrotizing vasculitis of small and medium sized arteries. We report a case of a 49-year old woman who presented with PAN following exposure to silicone breast implants. Although the relationship between silicone implants and connective tissue diseases has been investigated in the literature, no prior reports were found documenting PAN after silicone mammoplasty. While the pathogenesis of idiopathic PAN is not known yet, responsiveness to immunosuppressive therapy may suggest an immunologic mechanism. More robust research is needed to understand the connection between silicone breast implants and autoimmunity. Hindawi Publishing Corporation 2015 2015-12-30 /pmc/articles/PMC4710902/ /pubmed/26844000 http://dx.doi.org/10.1155/2015/765170 Text en Copyright © 2015 Yamen Homsi et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Homsi, Yamen
Carlson, John Andrew
Homsi, Samer
Polyarteritis Nodosa Presenting as Digital Gangrene and Breast Lesion following Exposure to Silicone Breast Implants
title Polyarteritis Nodosa Presenting as Digital Gangrene and Breast Lesion following Exposure to Silicone Breast Implants
title_full Polyarteritis Nodosa Presenting as Digital Gangrene and Breast Lesion following Exposure to Silicone Breast Implants
title_fullStr Polyarteritis Nodosa Presenting as Digital Gangrene and Breast Lesion following Exposure to Silicone Breast Implants
title_full_unstemmed Polyarteritis Nodosa Presenting as Digital Gangrene and Breast Lesion following Exposure to Silicone Breast Implants
title_short Polyarteritis Nodosa Presenting as Digital Gangrene and Breast Lesion following Exposure to Silicone Breast Implants
title_sort polyarteritis nodosa presenting as digital gangrene and breast lesion following exposure to silicone breast implants
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710902/
https://www.ncbi.nlm.nih.gov/pubmed/26844000
http://dx.doi.org/10.1155/2015/765170
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AT homsisamer polyarteritisnodosapresentingasdigitalgangreneandbreastlesionfollowingexposuretosiliconebreastimplants

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