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Mutanome Engineered RNA Immunotherapy: Towards Patient-Centered Tumor Vaccination

Advances in nucleic acid sequencing technologies have revolutionized the field of genomics, allowing the efficient targeting of mutated neoantigens for personalized cancer vaccination. Due to their absence during negative selection of T cells and their lack of expression in healthy tissue, tumor mut...

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Detalles Bibliográficos
Autores principales: Vormehr, Mathias, Schrörs, Barbara, Boegel, Sebastian, Löwer, Martin, Türeci, Özlem, Sahin, Ugur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710911/
https://www.ncbi.nlm.nih.gov/pubmed/26844233
http://dx.doi.org/10.1155/2015/595363