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Mutanome Engineered RNA Immunotherapy: Towards Patient-Centered Tumor Vaccination
Advances in nucleic acid sequencing technologies have revolutionized the field of genomics, allowing the efficient targeting of mutated neoantigens for personalized cancer vaccination. Due to their absence during negative selection of T cells and their lack of expression in healthy tissue, tumor mut...
Autores principales: | Vormehr, Mathias, Schrörs, Barbara, Boegel, Sebastian, Löwer, Martin, Türeci, Özlem, Sahin, Ugur |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710911/ https://www.ncbi.nlm.nih.gov/pubmed/26844233 http://dx.doi.org/10.1155/2015/595363 |
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