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A Case of Idiopathic Acute Pancreatitis in the First Trimester of Pregnancy

Acute pancreatitis is rare in pregnancy, with an estimated incidence of approximately 1 in 1000 to 1 in 10,000 pregnancies. Acute pancreatitis in pregnancy usually occurs in the third trimester. Here, we report a case of acute pancreatitis in the first trimester. A 36-year-old primigravida at 11 wee...

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Autores principales: Hara, Tomomi, Kanasaki, Haruhiko, Oride, Aki, Ishihara, Tomoko, Kyo, Satoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710924/
https://www.ncbi.nlm.nih.gov/pubmed/26843995
http://dx.doi.org/10.1155/2015/469527
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author Hara, Tomomi
Kanasaki, Haruhiko
Oride, Aki
Ishihara, Tomoko
Kyo, Satoru
author_facet Hara, Tomomi
Kanasaki, Haruhiko
Oride, Aki
Ishihara, Tomoko
Kyo, Satoru
author_sort Hara, Tomomi
collection PubMed
description Acute pancreatitis is rare in pregnancy, with an estimated incidence of approximately 1 in 1000 to 1 in 10,000 pregnancies. Acute pancreatitis in pregnancy usually occurs in the third trimester. Here, we report a case of acute pancreatitis in the first trimester. A 36-year-old primigravida at 11 weeks of gestation complained of severe lower abdominal pain. The pain gradually worsened and migrated toward the epigastric region. She had no history of chronic alcoholism. Blood investigations showed elevated level of C-reactive protein (9.58 mg/dL), pancreatic amylase (170 IU/L), and lipase (332 IU/L). There was no gallstone and no abnormality in the pancreatic and biliary ducts on ultrasonography. Antinuclear antibody and IgG4 were negative and no evidence of hyperlipidemia or diabetes was found. There was also no evidence of viral infection. On the third day of hospitalization, she was diagnosed with severe acute pancreatitis on magnetic resonance imaging. Medical interventions were initiated with nafamostat mesilate and ulinastatin, and parenteral nutrition was administered through a central venous catheter. On the eighth day of hospitalization, her condition gradually improved with a decreased level of pancreatic amylase and the pain subsided. After conservative management, she did not have any recurrence during her pregnancy.
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spelling pubmed-47109242016-02-03 A Case of Idiopathic Acute Pancreatitis in the First Trimester of Pregnancy Hara, Tomomi Kanasaki, Haruhiko Oride, Aki Ishihara, Tomoko Kyo, Satoru Case Rep Obstet Gynecol Case Report Acute pancreatitis is rare in pregnancy, with an estimated incidence of approximately 1 in 1000 to 1 in 10,000 pregnancies. Acute pancreatitis in pregnancy usually occurs in the third trimester. Here, we report a case of acute pancreatitis in the first trimester. A 36-year-old primigravida at 11 weeks of gestation complained of severe lower abdominal pain. The pain gradually worsened and migrated toward the epigastric region. She had no history of chronic alcoholism. Blood investigations showed elevated level of C-reactive protein (9.58 mg/dL), pancreatic amylase (170 IU/L), and lipase (332 IU/L). There was no gallstone and no abnormality in the pancreatic and biliary ducts on ultrasonography. Antinuclear antibody and IgG4 were negative and no evidence of hyperlipidemia or diabetes was found. There was also no evidence of viral infection. On the third day of hospitalization, she was diagnosed with severe acute pancreatitis on magnetic resonance imaging. Medical interventions were initiated with nafamostat mesilate and ulinastatin, and parenteral nutrition was administered through a central venous catheter. On the eighth day of hospitalization, her condition gradually improved with a decreased level of pancreatic amylase and the pain subsided. After conservative management, she did not have any recurrence during her pregnancy. Hindawi Publishing Corporation 2015 2015-12-30 /pmc/articles/PMC4710924/ /pubmed/26843995 http://dx.doi.org/10.1155/2015/469527 Text en Copyright © 2015 Tomomi Hara et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Hara, Tomomi
Kanasaki, Haruhiko
Oride, Aki
Ishihara, Tomoko
Kyo, Satoru
A Case of Idiopathic Acute Pancreatitis in the First Trimester of Pregnancy
title A Case of Idiopathic Acute Pancreatitis in the First Trimester of Pregnancy
title_full A Case of Idiopathic Acute Pancreatitis in the First Trimester of Pregnancy
title_fullStr A Case of Idiopathic Acute Pancreatitis in the First Trimester of Pregnancy
title_full_unstemmed A Case of Idiopathic Acute Pancreatitis in the First Trimester of Pregnancy
title_short A Case of Idiopathic Acute Pancreatitis in the First Trimester of Pregnancy
title_sort case of idiopathic acute pancreatitis in the first trimester of pregnancy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710924/
https://www.ncbi.nlm.nih.gov/pubmed/26843995
http://dx.doi.org/10.1155/2015/469527
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