IL-4 orchestrates STAT6-mediated DNA demethylation leading to dendritic cell differentiation

BACKGROUND: The role of cytokines in establishing specific transcriptional programmes in innate immune cells has long been recognized. However, little is known about how these extracellular factors instruct innate immune cell epigenomes to engage specific differentiation states. Human monocytes diff...

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Detalles Bibliográficos
Autores principales: Vento-Tormo, Roser, Company, Carlos, Rodríguez-Ubreva, Javier, de la Rica, Lorenzo, Urquiza, José M., Javierre, Biola M., Sabarinathan, Radhakrishnan, Luque, Ana, Esteller, Manel, Aran, Josep M., Álvarez-Errico, Damiana, Ballestar, Esteban
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711003/
https://www.ncbi.nlm.nih.gov/pubmed/26758199
http://dx.doi.org/10.1186/s13059-015-0863-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711003/
https://www.ncbi.nlm.nih.gov/pubmed/26758199
http://dx.doi.org/10.1186/s13059-015-0863-2

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