Hedgehog Acyltransferase as a target in estrogen receptor positive, HER2 amplified, and tamoxifen resistant breast cancer cells

BACKGROUND: Hedgehog acyltransferase (Hhat) catalyzes the transfer of the fatty acid palmitate onto Sonic Hedgehog (Shh), a modification that is essential for Shh signaling activity. The Shh signaling pathway has been implicated in the progression of breast cancer. METHODS: To determine the function...

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Detalles Bibliográficos
Autores principales: Matevossian, Armine, Resh, Marilyn D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711017/
https://www.ncbi.nlm.nih.gov/pubmed/25889650
http://dx.doi.org/10.1186/s12943-015-0345-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711017/
https://www.ncbi.nlm.nih.gov/pubmed/25889650
http://dx.doi.org/10.1186/s12943-015-0345-x

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