Cargando…

The human RNA surveillance factor UPF1 regulates tumorigenesis by targeting Smad7 in hepatocellular carcinoma

BACKGROUND: In spite of progress in diagnostics and treatment of Hepatocellular Carcinoma (HCC), its prognosis remains poor, and improved treatment strategies for HCC require detailed understanding of the underlying mechanism. In this investigation we studied the role of Up-frameshift 1 (UPF1) in th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chang, Lei, Li, Cuicui, Guo, Tao, Wang, Haitao, Ma, Weijie, Yuan, Yufeng, Liu, Quanyan, Ye, Qifa, Liu, Zhisu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711019/ https://www.ncbi.nlm.nih.gov/pubmed/26759305 http://dx.doi.org/10.1186/s13046-016-0286-2

Ejemplares similares

The C/D box small nucleolar RNA SNORD52 regulated by Upf1 facilitates Hepatocarcinogenesis by stabilizing CDK1
por: Li, Cuicui, et al.
Publicado: (2020)

Decreased expression of long non-coding RNA GAS5 indicates a poor prognosis and promotes cell proliferation and invasion in hepatocellular carcinoma by regulating vimentin
por: CHANG, LEI, et al.
Publicado: (2016)

Long non‐coding RNA SNAI3‐AS1 promotes the proliferation and metastasis of hepatocellular carcinoma by regulating the UPF1/Smad7 signalling pathway
por: Li, Yarui, et al.
Publicado: (2019)

GAS5 protects against osteoporosis by targeting UPF1/SMAD7 axis in osteoblast differentiation
por: Li, Ming, et al.
Publicado: (2020)

Feasibility and Efficacy of S-Adenosyl-L-methionine in Patients with HBV-Related HCC with Different BCLC Stages
por: Guo, Tao, et al.
Publicado: (2016)

Correction to Long non‐coding RNA SNAI3‐AS1 promotes the proliferation and metastasis of hepatocellular carcinoma by regulating the UPF1/Smad7 signalling pathway
Publicado: (2023)

Cancer cell membrane-camouflaged MOF nanoparticles for a potent dihydroartemisinin-based hepatocellular carcinoma therapy
por: Xiao, Yusha, et al.
Publicado: (2020)

The UPF1 RNA Surveillance Gene is Commonly Mutated in Pancreatic Adenosquamous Carcinoma
por: Liu, Chen, et al.
Publicado: (2014)

Identification of 13 Key Genes Correlated With Progression and Prognosis in Hepatocellular Carcinoma by Weighted Gene Co-expression Network Analysis
por: Gu, Yang, et al.
Publicado: (2020)

Human Endogenous Retroviruses-K (HML-2) Expression Is Correlated with Prognosis and Progress of Hepatocellular Carcinoma
por: Ma, Weijie, et al.
Publicado: (2016)

A novel microRNA miR-MTCO3P38 inhibits malignant progression via STAT3/PTTG1/MYC in hepatocellular carcinoma
por: Guo, Deliang, et al.
Publicado: (2021)

Lgr5-mediated p53 Repression through PDCD5 leads to doxorubicin resistance in Hepatocellular Carcinoma
por: Ma, Zhili, et al.
Publicado: (2019)

The feedback control of UPF3 is crucial for RNA surveillance in plants
por: Degtiar, Evgeniya, et al.
Publicado: (2015)

RBM47 inhibits hepatocellular carcinoma progression by targeting UPF1 as a DNA/RNA regulator
por: Guo, Tao, et al.
Publicado: (2022)

The RNA surveillance proteins UPF1, UPF2 and SMG6 affect HIV-1 reactivation at a post-transcriptional level
por: Rao, Shringar, et al.
Publicado: (2018)

Nuclear UPF1 Is Associated with Chromatin for Transcription-Coupled RNA Surveillance
por: Hong, Dawon, et al.
Publicado: (2019)

UPF1: From mRNA Surveillance to Protein Quality Control
por: Hwang, Hyun Jung, et al.
Publicado: (2021)

Short- and Long-Term Outcomes of Indocyanine Green Fluorescence Navigation- Versus Conventional-Laparoscopic Hepatectomy for Hepatocellular Carcinoma: A Propensity Score-Matched, Retrospective, Cohort Study
por: Liu, Fusheng, et al.
Publicado: (2023)

UPF1 inhibits the hepatocellular carcinoma progression by targeting long non-coding RNA UCA1
por: Zhou, Yongli, et al.
Publicado: (2019)

UPF1 Inhibits Hepatocellular Carcinoma Growth through DUSP1/p53 Signal Pathway
por: Lee, Suman, et al.
Publicado: (2022)

Aberrant expression of the UPF1 RNA surveillance gene disturbs keratinocyte homeostasis by stabilizing AREG
por: Cheng, Yaojia, et al.
Publicado: (2020)

Rather than Rs1800796 Polymorphism, Expression of Interleukin-6 is Associated with Disease Progression of Chronic HBV Infection in a Chinese Han Population
por: Tang, Shengli, et al.
Publicado: (2013)

Identification and functional analysis of novel phosphorylation sites in the RNA surveillance protein Upf1
por: Lasalde, Clarivel, et al.
Publicado: (2014)

The origins and consequences of UPF1 variants in pancreatic adenosquamous carcinoma
por: Polaski, Jacob T, et al.
Publicado: (2021)

UPF1 contributes to the maintenance of endometrial cancer stem cell phenotype by stabilizing LINC00963
por: Chen, Hao, et al.
Publicado: (2022)

Skull base metastases from a malignant solitary fibrous tumor of the liver. A case report and literature review
por: Peng, Lu, et al.
Publicado: (2011)

DNASE1L3 arrests tumor angiogenesis by impairing the senescence-associated secretory phenotype in response to stress
por: Guo, Deliang, et al.
Publicado: (2021)

ATXN7L3 positively regulates SMAD7 transcription in hepatocellular carcinoma with growth inhibitory function
por: Sun, Ning, et al.
Publicado: (2020)

HIV-1 Recruits UPF1 but Excludes UPF2 to Promote Nucleocytoplasmic Export of the Genomic RNA
por: Ajamian, Lara, et al.
Publicado: (2015)

Serum deprivation-response protein induces apoptosis in hepatocellular carcinoma through ASK1-JNK/p38 MAPK pathways
por: Chen, Xi, et al.
Publicado: (2021)

Mixed Neuroendocrine Carcinoma and Hepatocellular Carcinoma: A Case Report and Literature Review
por: Lan, Jianwei, et al.
Publicado: (2021)

UPF1/SMG7-dependent microRNA-mediated gene regulation
por: Park, Jungyun, et al.
Publicado: (2019)

Ribosome-bound Upf1 forms distinct 80S complexes and conducts mRNA surveillance
por: Ganesan, Robin, et al.
Publicado: (2022)

LncRNA CASC2 Regulate Cell Proliferation and Invasion by Targeting miR-155/SOCS1 Axis in Hepatocellular Carcinoma
por: Yuan, Ye, et al.
Publicado: (2023)

MiR-21-3p Promotes Hepatocellular Carcinoma Progression via SMAD7/YAP1 Regulation
por: Hong, Yinghui, et al.
Publicado: (2021)

Up-regulation of CDK16 by multiple mechanisms in hepatocellular carcinoma promotes tumor progression
por: Wang, Yitao, et al.
Publicado: (2017)

METTL3-induced lncRNA GBAP1 promotes hepatocellular carcinoma progression by activating BMP/SMAD pathway
por: Liu, Runkun, et al.
Publicado: (2023)

The Plasma S-adenosylmethionine Level is Associated With the Severity of Hepatitis B-Related Liver Disease
por: Li, Ting, et al.
Publicado: (2015)

Deoxyribonuclease 1-like 3 Inhibits Hepatocellular Carcinoma Progression by Inducing Apoptosis and Reprogramming Glucose Metabolism
por: Xiao, Yusha, et al.
Publicado: (2022)

Insights into the Effects of Cancer Associated Mutations at the UPF2 and ATP-Binding Sites of NMD Master Regulator: UPF1
por: Kalathiya, Umesh, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_of9r1q79p6i043gfsat54qfeoq