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The human RNA surveillance factor UPF1 regulates tumorigenesis by targeting Smad7 in hepatocellular carcinoma

BACKGROUND: In spite of progress in diagnostics and treatment of Hepatocellular Carcinoma (HCC), its prognosis remains poor, and improved treatment strategies for HCC require detailed understanding of the underlying mechanism. In this investigation we studied the role of Up-frameshift 1 (UPF1) in th...

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Detalles Bibliográficos
Autores principales:	Chang, Lei, Li, Cuicui, Guo, Tao, Wang, Haitao, Ma, Weijie, Yuan, Yufeng, Liu, Quanyan, Ye, Qifa, Liu, Zhisu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711019/ https://www.ncbi.nlm.nih.gov/pubmed/26759305 http://dx.doi.org/10.1186/s13046-016-0286-2

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