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Prevalence of depression in Parkinson’s disease patients in Ethiopia

BACKGROUND: Parkinson’s disease (PD) is associated with cognitive and psychiatric disturbances including depression, anxiety, psychotic symptoms and sleep disturbances. These psychiatric manifestations have a negative impact on disease course and the medical management of PD patients. Major depressi...

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Autores principales: Worku, Dawit Kibru, Yifru, Yared Mamushet, Postels, Douglas G, Gashe, Fikre Enquselassie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711030/
https://www.ncbi.nlm.nih.gov/pubmed/26788336
http://dx.doi.org/10.1186/s40734-014-0010-3
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author Worku, Dawit Kibru
Yifru, Yared Mamushet
Postels, Douglas G
Gashe, Fikre Enquselassie
author_facet Worku, Dawit Kibru
Yifru, Yared Mamushet
Postels, Douglas G
Gashe, Fikre Enquselassie
author_sort Worku, Dawit Kibru
collection PubMed
description BACKGROUND: Parkinson’s disease (PD) is associated with cognitive and psychiatric disturbances including depression, anxiety, psychotic symptoms and sleep disturbances. These psychiatric manifestations have a negative impact on disease course and the medical management of PD patients. Major depression has a greater negative impact on patients’ quality of life than abnormal motor function, and is associated with faster cognitive decline and progression of motor deficits. Thus, the objective of this study was to determine the prevalence and pattern of depression in PD outpatients in Ethiopia. We determined the age range in which depression in PD patients is most common, the most common symptoms of depression, and the epidemiologic confounders associated with depression in PD patients. METHODS: We conducted a cross-sectional point prevalence study of all PD patients attending the follow-up clinics of the departments of neurology at Black Lion Teaching and Zewuditu Memorial Hospitals in Addis Ababa, Ethiopia, from May 2013 to August 2013. We collected information using a structured questionnaire which assessed demographic information, clinical history, and neurologic function. RESULT: Of the 101 patients surveyed, the prevalence of depression was 58/101(57.4%). Of these patients, 1 of 58(1.7%) was on antidepressant medications. These low proportions likely indicate a low index of suspicion and under treatment of depression in PD outpatients. CONCLUSION: In Ethiopian PD outpatients, depression is under recognized and undertreated. We recommend routine use of screening tools. In those who screen positive for depression, treatment is warranted. Further studies are needed to confirm these findings, and to increase our understanding of specific signs and symptoms of depression in the context of PD. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s40734-014-0010-3) contains supplementary material, which is available to authorized users.
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spelling pubmed-47110302016-01-19 Prevalence of depression in Parkinson’s disease patients in Ethiopia Worku, Dawit Kibru Yifru, Yared Mamushet Postels, Douglas G Gashe, Fikre Enquselassie J Clin Mov Disord Research Article BACKGROUND: Parkinson’s disease (PD) is associated with cognitive and psychiatric disturbances including depression, anxiety, psychotic symptoms and sleep disturbances. These psychiatric manifestations have a negative impact on disease course and the medical management of PD patients. Major depression has a greater negative impact on patients’ quality of life than abnormal motor function, and is associated with faster cognitive decline and progression of motor deficits. Thus, the objective of this study was to determine the prevalence and pattern of depression in PD outpatients in Ethiopia. We determined the age range in which depression in PD patients is most common, the most common symptoms of depression, and the epidemiologic confounders associated with depression in PD patients. METHODS: We conducted a cross-sectional point prevalence study of all PD patients attending the follow-up clinics of the departments of neurology at Black Lion Teaching and Zewuditu Memorial Hospitals in Addis Ababa, Ethiopia, from May 2013 to August 2013. We collected information using a structured questionnaire which assessed demographic information, clinical history, and neurologic function. RESULT: Of the 101 patients surveyed, the prevalence of depression was 58/101(57.4%). Of these patients, 1 of 58(1.7%) was on antidepressant medications. These low proportions likely indicate a low index of suspicion and under treatment of depression in PD outpatients. CONCLUSION: In Ethiopian PD outpatients, depression is under recognized and undertreated. We recommend routine use of screening tools. In those who screen positive for depression, treatment is warranted. Further studies are needed to confirm these findings, and to increase our understanding of specific signs and symptoms of depression in the context of PD. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s40734-014-0010-3) contains supplementary material, which is available to authorized users. BioMed Central 2014-12-12 /pmc/articles/PMC4711030/ /pubmed/26788336 http://dx.doi.org/10.1186/s40734-014-0010-3 Text en © Worku et al.; licensee BioMed Central Ltd. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Worku, Dawit Kibru
Yifru, Yared Mamushet
Postels, Douglas G
Gashe, Fikre Enquselassie
Prevalence of depression in Parkinson’s disease patients in Ethiopia
title Prevalence of depression in Parkinson’s disease patients in Ethiopia
title_full Prevalence of depression in Parkinson’s disease patients in Ethiopia
title_fullStr Prevalence of depression in Parkinson’s disease patients in Ethiopia
title_full_unstemmed Prevalence of depression in Parkinson’s disease patients in Ethiopia
title_short Prevalence of depression in Parkinson’s disease patients in Ethiopia
title_sort prevalence of depression in parkinson’s disease patients in ethiopia
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711030/
https://www.ncbi.nlm.nih.gov/pubmed/26788336
http://dx.doi.org/10.1186/s40734-014-0010-3
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