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Radix puerariae extracts ameliorate paraquat-induced pulmonary fibrosis by attenuating follistatin-like 1 and nuclear factor erythroid 2p45-related factor-2 signalling pathways through downregulation of miRNA-21 expression

BACKGROUND: Puerarin, extracted from Radix puerariae, was reported to ameliorate airway inflammation, lung injury and lung fibrosis induced by paraquat (PQ) in mice. However, effects of Radix puerariae extracts (RPEs) on lung fibrosis or signalling pathways in PQ-induced lung injury have not been we...

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Detalles Bibliográficos
Autores principales: Liu, Ming-wei, Liu, Rong, Wu, Hai-ying, Li, Yi-yun, Su, Mei-xian, Dong, Min-na, Zhang, Wei, Qian, Chuan-yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711072/
https://www.ncbi.nlm.nih.gov/pubmed/26758514
http://dx.doi.org/10.1186/s12906-016-0991-6

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