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Radix puerariae extracts ameliorate paraquat-induced pulmonary fibrosis by attenuating follistatin-like 1 and nuclear factor erythroid 2p45-related factor-2 signalling pathways through downregulation of miRNA-21 expression
BACKGROUND: Puerarin, extracted from Radix puerariae, was reported to ameliorate airway inflammation, lung injury and lung fibrosis induced by paraquat (PQ) in mice. However, effects of Radix puerariae extracts (RPEs) on lung fibrosis or signalling pathways in PQ-induced lung injury have not been we...
Autores principales: | Liu, Ming-wei, Liu, Rong, Wu, Hai-ying, Li, Yi-yun, Su, Mei-xian, Dong, Min-na, Zhang, Wei, Qian, Chuan-yun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711072/ https://www.ncbi.nlm.nih.gov/pubmed/26758514 http://dx.doi.org/10.1186/s12906-016-0991-6 |
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