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Early and gender-specific differences in spinal cord mitochondrial function and oxidative stress markers in a mouse model of ALS

INTRODUCTION: Amyotrophic lateral sclerosis (ALS) is a motor neuron disease with a gender bias towards major prevalence in male individuals. Several data suggest the involvement of oxidative stress and mitochondrial dysfunction in its pathogenesis, though differences between genders have not been ev...

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Detalles Bibliográficos
Autores principales: Cacabelos, Daniel, Ramírez-Núñez, Omar, Granado-Serrano, Ana Belén, Torres, Pascual, Ayala, Victòria, Moiseeva, Victoria, Povedano, Mònica, Ferrer, Isidre, Pamplona, Reinald, Portero-Otin, Manuel, Boada, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711180/
https://www.ncbi.nlm.nih.gov/pubmed/26757991
http://dx.doi.org/10.1186/s40478-015-0271-6