Four hepatosplenic T-cell lymphoma cases of Japanese patients

Hepatosplenic T-cell lymphoma (HSTCL), a rare type of γδ T-cell lymphoma, is characterized by hepatosplenomegaly and cytopenias. It is associated with immunodeficiency and its age of onset is reportedly between the 20s and 30s. We herein report 4 Japanese HSTCL cases. Three of them, including an eld...

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Detalles Bibliográficos
Autores principales: Kawai, Hidetsugu, Matsushita, Hiromichi, Ohmachi, Ken, Kojima, Minoru, Machida, Shinichiro, Ogawa, Yoshiaki, Kawada, Hiroshi, Nakamura, Naoya, Ando, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711307/
https://www.ncbi.nlm.nih.gov/pubmed/26870659
http://dx.doi.org/10.1016/j.lrr.2015.12.001
Descripción
Sumario:Hepatosplenic T-cell lymphoma (HSTCL), a rare type of γδ T-cell lymphoma, is characterized by hepatosplenomegaly and cytopenias. It is associated with immunodeficiency and its age of onset is reportedly between the 20s and 30s. We herein report 4 Japanese HSTCL cases. Three of them, including an elderly case that was 74 years of age, were not at adolescence. No cases had a history of immunodeficiency. All other disease phenotypes were similar to the typical HSTCL cases. These findings suggest that there are a certain proportion of HSTCL patients who presented after middle age.

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