Four hepatosplenic T-cell lymphoma cases of Japanese patients

Hepatosplenic T-cell lymphoma (HSTCL), a rare type of γδ T-cell lymphoma, is characterized by hepatosplenomegaly and cytopenias. It is associated with immunodeficiency and its age of onset is reportedly between the 20s and 30s. We herein report 4 Japanese HSTCL cases. Three of them, including an eld...

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Autores principales: Kawai, Hidetsugu, Matsushita, Hiromichi, Ohmachi, Ken, Kojima, Minoru, Machida, Shinichiro, Ogawa, Yoshiaki, Kawada, Hiroshi, Nakamura, Naoya, Ando, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711307/
https://www.ncbi.nlm.nih.gov/pubmed/26870659
http://dx.doi.org/10.1016/j.lrr.2015.12.001
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author Kawai, Hidetsugu
Matsushita, Hiromichi
Ohmachi, Ken
Kojima, Minoru
Machida, Shinichiro
Ogawa, Yoshiaki
Kawada, Hiroshi
Nakamura, Naoya
Ando, Kiyoshi
author_facet Kawai, Hidetsugu
Matsushita, Hiromichi
Ohmachi, Ken
Kojima, Minoru
Machida, Shinichiro
Ogawa, Yoshiaki
Kawada, Hiroshi
Nakamura, Naoya
Ando, Kiyoshi
author_sort Kawai, Hidetsugu
collection PubMed
description Hepatosplenic T-cell lymphoma (HSTCL), a rare type of γδ T-cell lymphoma, is characterized by hepatosplenomegaly and cytopenias. It is associated with immunodeficiency and its age of onset is reportedly between the 20s and 30s. We herein report 4 Japanese HSTCL cases. Three of them, including an elderly case that was 74 years of age, were not at adolescence. No cases had a history of immunodeficiency. All other disease phenotypes were similar to the typical HSTCL cases. These findings suggest that there are a certain proportion of HSTCL patients who presented after middle age.
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spelling pubmed-47113072016-02-11 Four hepatosplenic T-cell lymphoma cases of Japanese patients Kawai, Hidetsugu Matsushita, Hiromichi Ohmachi, Ken Kojima, Minoru Machida, Shinichiro Ogawa, Yoshiaki Kawada, Hiroshi Nakamura, Naoya Ando, Kiyoshi Leuk Res Rep Case Report Hepatosplenic T-cell lymphoma (HSTCL), a rare type of γδ T-cell lymphoma, is characterized by hepatosplenomegaly and cytopenias. It is associated with immunodeficiency and its age of onset is reportedly between the 20s and 30s. We herein report 4 Japanese HSTCL cases. Three of them, including an elderly case that was 74 years of age, were not at adolescence. No cases had a history of immunodeficiency. All other disease phenotypes were similar to the typical HSTCL cases. These findings suggest that there are a certain proportion of HSTCL patients who presented after middle age. Elsevier 2015-12-15 /pmc/articles/PMC4711307/ /pubmed/26870659 http://dx.doi.org/10.1016/j.lrr.2015.12.001 Text en © 2015 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Kawai, Hidetsugu
Matsushita, Hiromichi
Ohmachi, Ken
Kojima, Minoru
Machida, Shinichiro
Ogawa, Yoshiaki
Kawada, Hiroshi
Nakamura, Naoya
Ando, Kiyoshi
Four hepatosplenic T-cell lymphoma cases of Japanese patients
title Four hepatosplenic T-cell lymphoma cases of Japanese patients
title_full Four hepatosplenic T-cell lymphoma cases of Japanese patients
title_fullStr Four hepatosplenic T-cell lymphoma cases of Japanese patients
title_full_unstemmed Four hepatosplenic T-cell lymphoma cases of Japanese patients
title_short Four hepatosplenic T-cell lymphoma cases of Japanese patients
title_sort four hepatosplenic t-cell lymphoma cases of japanese patients
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711307/
https://www.ncbi.nlm.nih.gov/pubmed/26870659
http://dx.doi.org/10.1016/j.lrr.2015.12.001
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