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Statistical Evaluation of HTS Assays for Enzymatic Hydrolysis of β-Keto Esters
β-keto esters are used as precursors for the synthesis of β-amino acids, which are building blocks for some classes of pharmaceuticals. Here we describe the comparison of screening procedures for hydrolases to be used for the hydrolysis of β-keto esters, the first step in the preparation of β-amino...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711668/ https://www.ncbi.nlm.nih.gov/pubmed/26730596 http://dx.doi.org/10.1371/journal.pone.0146104 |