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Statistical Evaluation of HTS Assays for Enzymatic Hydrolysis of β-Keto Esters
β-keto esters are used as precursors for the synthesis of β-amino acids, which are building blocks for some classes of pharmaceuticals. Here we describe the comparison of screening procedures for hydrolases to be used for the hydrolysis of β-keto esters, the first step in the preparation of β-amino...
Autores principales: | Buß, O., Jager, S., Dold, S. -M., Zimmermann, S., Hamacher, K., Schmitz, K., Rudat, J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711668/ https://www.ncbi.nlm.nih.gov/pubmed/26730596 http://dx.doi.org/10.1371/journal.pone.0146104 |
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