Regulation of Rac1 and Reactive Oxygen Species Production in Response to Infection of Gastrointestinal Epithelia

Generation of reactive oxygen species (ROS) during infection is an immediate host defense leading to microbial killing. APE1 is a multifunctional protein induced by ROS and after induction, protects against ROS-mediated DNA damage. Rac1 and NAPDH oxidase (Nox1) are important contributors of ROS gene...

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Detalles Bibliográficos
Autores principales: den Hartog, Gerco, Chattopadhyay, Ranajoy, Ablack, Amber, Hall, Emily H., Butcher, Lindsay D., Bhattacharyya, Asima, Eckmann, Lars, Harris, Paul R., Das, Soumita, Ernst, Peter B., Crowe, Sheila E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711900/
https://www.ncbi.nlm.nih.gov/pubmed/26761793
http://dx.doi.org/10.1371/journal.ppat.1005382

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