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Strong Expression of Hypoxia-Inducible Factor-1α (HIF-1α) Is Associated with Axl Expression and Features of Aggressive Tumors in African Breast Cancer

PURPOSE: Inhibition of hypoxia-inducible factor (HIF) and Axl receptor tyrosine kinase is being evaluated for targeted therapy in solid tumors. Both HIF-1α and Axl influence tumor growth and metastatic potential, and they have been linked to treatment failure in many cancers. However, there is a lac...

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Detalles Bibliográficos
Autores principales:	Nalwoga, Hawa, Ahmed, Lavina, Arnes, Jarle B., Wabinga, Henry, Akslen, Lars A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711940/ https://www.ncbi.nlm.nih.gov/pubmed/26760782 http://dx.doi.org/10.1371/journal.pone.0146823

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