Identification of miR-148a as a novel regulator of cholesterol metabolism

The hepatic low-density lipoprotein receptor (LDLR) pathway is essential for clearing circulating LDL-cholesterol (LDL-C). While the transcriptional regulation of LDLR is well-characterized, the post-transcriptional mechanisms which govern LDLR expression are just beginning to emerge. Here, we devel...

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Detalles Bibliográficos
Autores principales: Goedeke, Leigh, Rotllan, Noemi, Canfrán-Duque, Alberto, Aranda, Juan F., Ramírez, Cristina M., Araldi, Elisa, Lin, Chin-Sheng, Anderson, Norma N., Wagschal, Alexandre, de Cabo, Rafael, Horton, Jay D., Lasunción, Miguel A., Näär, Anders M., Suárez, Yajaira, Fernández-Hernando, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711995/
https://www.ncbi.nlm.nih.gov/pubmed/26437365
http://dx.doi.org/10.1038/nm.3949

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