Cargando…
Targeting Aberrant Epigenetic Networks Mediated by PRMT1 and KDM4C in Acute Myeloid Leukemia
Transcriptional deregulation plays a major role in acute myeloid leukemia, and therefore identification of epigenetic modifying enzymes essential for the maintenance of oncogenic transcription programs holds the key to better understanding of the biology and designing effective therapeutic strategie...
Autores principales: | Cheung, Ngai, Fung, Tsz Kan, Zeisig, Bernd B., Holmes, Katie, Rane, Jayant K., Mowen, Kerri A., Finn, Michael G., Lenhard, Boris, Chan, Li Chong, So, Chi Wai Eric |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712026/ https://www.ncbi.nlm.nih.gov/pubmed/26766589 http://dx.doi.org/10.1016/j.ccell.2015.12.007 |
Ejemplares similares
-
Overcoming treatment resistance in acute promyelocytic leukemia and beyond
por: Fung, Tsz Kan, et al.
Publicado: (2013) -
Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer
por: Blair, Lauren P., et al.
Publicado: (2011) -
PRMT1 loss sensitizes cells to PRMT5 inhibition
por: Gao, Guozhen, et al.
Publicado: (2019) -
The KDM4A/KDM4C/NF-κB and WDR5 epigenetic cascade regulates the activation of B cells
por: Hung, Kuo-Hsuan, et al.
Publicado: (2018) -
Histone demethylase KDM4C controls tumorigenesis of glioblastoma by epigenetically regulating p53 and c-Myc
por: Lee, Dong Hoon, et al.
Publicado: (2021)