Inhibition of Contractile Function in Human Joint Capsule Myofibroblasts by Targeting the TGF-β1 and PDGF Pathways

BACKGROUND: Contractile myofibroblasts (MFs) accumulate in the joint capsules of patients suffering from posttraumatic joint stiffness. MF activation is controlled by a complex local network of growth factors and cytokines, ending in the increased production of extracellular matrix components follow...

Descripción completa

Detalles Bibliográficos
Autores principales: Mattyasovszky, Stefan G., Wollstädter, Jochen, Martin, Anne, Ritz, Ulrike, Baranowski, Andreas, Ossendorf, Christian, Rommens, Pol M., Hofmann, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712129/
https://www.ncbi.nlm.nih.gov/pubmed/26730954
http://dx.doi.org/10.1371/journal.pone.0145948

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712129/
https://www.ncbi.nlm.nih.gov/pubmed/26730954
http://dx.doi.org/10.1371/journal.pone.0145948

Ejemplares similares