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Inhibition of Contractile Function in Human Joint Capsule Myofibroblasts by Targeting the TGF-β1 and PDGF Pathways

BACKGROUND: Contractile myofibroblasts (MFs) accumulate in the joint capsules of patients suffering from posttraumatic joint stiffness. MF activation is controlled by a complex local network of growth factors and cytokines, ending in the increased production of extracellular matrix components follow...

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Detalles Bibliográficos
Autores principales:	Mattyasovszky, Stefan G., Wollstädter, Jochen, Martin, Anne, Ritz, Ulrike, Baranowski, Andreas, Ossendorf, Christian, Rommens, Pol M., Hofmann, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712129/ https://www.ncbi.nlm.nih.gov/pubmed/26730954 http://dx.doi.org/10.1371/journal.pone.0145948

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