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Osteopontin That Is Elevated in the Airways during COPD Impairs the Antibacterial Activity of Common Innate Antibiotics

Bacterial infections of the respiratory tract contribute to exacerbations and disease progression in chronic obstructive pulmonary disease (COPD). There is also an increased risk of invasive pneumococcal disease in COPD. The underlying mechanisms are not fully understood but include impaired mucocil...

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Detalles Bibliográficos
Autores principales: Gela, Anele, Bhongir, Ravi K. V., Mori, Michiko, Keenan, Paul, Mörgelin, Matthias, Erjefält, Jonas S., Herwald, Heiko, Egesten, Arne, Kasetty, Gopinath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712133/
https://www.ncbi.nlm.nih.gov/pubmed/26731746
http://dx.doi.org/10.1371/journal.pone.0146192