Cargando…

Osteopontin That Is Elevated in the Airways during COPD Impairs the Antibacterial Activity of Common Innate Antibiotics

Bacterial infections of the respiratory tract contribute to exacerbations and disease progression in chronic obstructive pulmonary disease (COPD). There is also an increased risk of invasive pneumococcal disease in COPD. The underlying mechanisms are not fully understood but include impaired mucocil...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gela, Anele, Bhongir, Ravi K. V., Mori, Michiko, Keenan, Paul, Mörgelin, Matthias, Erjefält, Jonas S., Herwald, Heiko, Egesten, Arne, Kasetty, Gopinath
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712133/ https://www.ncbi.nlm.nih.gov/pubmed/26731746 http://dx.doi.org/10.1371/journal.pone.0146192

Ejemplares similares

Osteopontin Expression in Small Airway Epithelium in Copd is Dependent on Differentiation and Confined to Subsets of Cells
por: Ali, Mohamad N., et al.
Publicado: (2019)

Author Correction: Osteopontin Expression in Small Airway Epithelium in Copd is Dependent on Differentiation and Confined to Subsets of Cells
por: Ali, Mohamad N., et al.
Publicado: (2020)

An ecoimmunological approach to study evolutionary and ancient links between coagulation, complement and Innate immunity
por: Papareddy, Praveen, et al.
Publicado: (2018)

TFPI-2 Protects Against Gram-Negative Bacterial Infection
por: Ali, Mohamad N., et al.
Publicado: (2018)

Zoledronic Acid Targeting of the Mevalonate Pathway Causes Reduced Cell Recruitment and Attenuates Pulmonary Fibrosis
por: Tanner, Lloyd, et al.
Publicado: (2022)

Pseudomonas aeruginosa elastase cleaves a C-terminal peptide from human thrombin that inhibits host inflammatory responses
por: van der Plas, Mariena J. A., et al.
Publicado: (2016)

Small airway epithelial-C/EBPβ is increased in patients with advanced COPD
por: Mori, Michiko, et al.
Publicado: (2015)

Pharmacological OGG1 inhibition decreases murine allergic airway inflammation
por: Tanner, Lloyd, et al.
Publicado: (2022)

Extracellular Histones Induce Chemokine Production in Whole Blood Ex Vivo and Leukocyte Recruitment In Vivo
por: Westman, Johannes, et al.
Publicado: (2015)

Tartrate resistant acid phosphatase 5 (TRAP5) mediates immune cell recruitment in a murine model of pulmonary bacterial infection
por: Tanner, Lloyd, et al.
Publicado: (2022)

SpeB of Streptococcus pyogenes Differentially Modulates Antibacterial and Receptor Activating Properties of Human Chemokines
por: Egesten, Arne, et al.
Publicado: (2009)

SufA of the Opportunistic Pathogen Finegoldia magna Modulates Actions of the Antibacterial Chemokine MIG/CXCL9, Promoting Bacterial Survival during Epithelial Inflammation
por: Karlsson, Christofer, et al.
Publicado: (2009)

M protein from Streptococcus pyogenes induces tissue factor expression and pro-coagulant activity in human monocytes
por: Påhlman, Lisa I., et al.
Publicado: (2007)

Pathogen Entrapment by Transglutaminase—A Conserved Early Innate Immune Mechanism
por: Wang, Zhi, et al.
Publicado: (2010)

Increased number and altered phenotype of lymphatic vessels in peripheral lung compartments of patients with COPD
por: Mori, Michiko, et al.
Publicado: (2013)

The Pulmonary Extracellular Matrix Is a Bactericidal Barrier Against Haemophilus influenzae in Chronic Obstructive Pulmonary Disease (COPD): Implications for an in vivo Innate Host Defense Function of Collagen VI
por: Abdillahi, Suado M., et al.
Publicado: (2018)

Corrigendum: The pulmonary extracellular matrix is a bactericidal barrier against Haemophilus influenzae in chronic obstructive pulmonary disease (COPD): implications for an in vivo innate host defense function of collagen VI
por: Abdillahi, Suado M., et al.
Publicado: (2023)

Severe Lung Lesions Caused by Salmonella Are Prevented by Inhibition of the Contact System
por: Persson, Kristin, et al.
Publicado: (2000)

Hypoxia down-regulates expression of secretory leukocyte protease inhibitor in bronchial epithelial cells via TGF-β1
por: Påhlman, Lisa I, et al.
Publicado: (2015)

Plasma Protein Layer Concealment Protects Streptococcus pyogenes From Innate Immune Attack
por: Jagau, Hilger, et al.
Publicado: (2021)

Human Chemokines as Antimicrobial Peptides with Direct Parasiticidal Effect on Leishmania mexicana In Vitro
por: Söbirk, Sara K., et al.
Publicado: (2013)

Corrigendum: Plasma Protein Layer Concealment Protects Streptococcus pyogenes From Innate Immune Attack
por: Jagau, Hilger, et al.
Publicado: (2021)

Osteopontin Bridging Innate and Adaptive Immunity in Autoimmune Diseases
por: Clemente, Nausicaa, et al.
Publicado: (2016)

The Role and Clinical Relevance of Osteopontin in Allergic Airway Diseases
por: Liu, Yang, et al.
Publicado: (2023)

Secreted Osteopontin Is Highly Polymerized in Human Airways and Fragmented in Asthmatic Airway Secretions
por: Arjomandi, Mehrdad, et al.
Publicado: (2011)

COPD and the Risk of Tuberculosis - A Population-Based Cohort Study
por: Inghammar, Malin, et al.
Publicado: (2010)

A Novel Role for Pro-Coagulant Microvesicles in the Early Host Defense against Streptococcus pyogenes
por: Oehmcke, Sonja, et al.
Publicado: (2013)

Mast cells in human airways: the culprit?
por: Erjefält, Jonas S.
Publicado: (2014)

How Do Innate Immune Cells Contribute to Airway Remodeling in COPD Progression?
por: Bu, Tegeleqi, et al.
Publicado: (2020)

A Peptide of Heparin Cofactor II Inhibits Endotoxin-Mediated Shock and Invasive Pseudomonas aeruginosa Infection
por: Kalle, Martina, et al.
Publicado: (2014)

Antibodies against a Surface Protein of Streptococcus pyogenes Promote a Pathological Inflammatory Response
por: Kahn, Fredrik, et al.
Publicado: (2008)

Modulation of Hemostatic and Inflammatory Responses by Leptospira Spp.
por: Vieira, Mônica L., et al.
Publicado: (2016)

Osteopontin mediated eosinophils activation by group II innate lymphoid cells
por: Zeng, Qingxiang, et al.
Publicado: (2022)

Neutrophil extracellular trap-microparticle complexes enhance thrombin generation via the intrinsic pathway of coagulation in mice
por: Wang, Yongzhi, et al.
Publicado: (2018)

Increased IL-17RA and IL-17RC in End-Stage COPD and the Contribution to Mast Cell Secretion of FGF-2 and VEGF
por: Roos, Abraham B., et al.
Publicado: (2017)

Eosinophils, basophils and type 2 immune microenvironments in COPD-affected lung tissue
por: Jogdand, Prajakta, et al.
Publicado: (2020)

Intracellular osteopontin stabilizes TRAF3 to positively regulate innate antiviral response
por: Zhao, Kai, et al.
Publicado: (2016)

Broad Th2 neutralization and anti‐inflammatory action of pentosan polysulfate sodium in experimental allergic rhinitis
por: Sanden, Caroline, et al.
Publicado: (2017)

Apocalypse Now
por: Herwald, Heiko
Publicado: (2020)

IL-18 associated with lung lymphoid aggregates drives IFNγ production in severe COPD
por: Briend, Emmanuel, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_nd0lva7m24apg3nc9a08vaj0uj