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UIS2: A Unique Phosphatase Required for the Development of Plasmodium Liver Stages

Plasmodium salivary sporozoites are the infectious form of the malaria parasite and are dormant inside salivary glands of Anopheles mosquitoes. During dormancy, protein translation is inhibited by the kinase UIS1 that phosphorylates serine 59 in the eukaryotic initiation factor 2α (eIF2α). De-phosph...

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Detalles Bibliográficos
Autores principales: Zhang, Min, Mishra, Satish, Sakthivel, Ramanavelan, Fontoura, Beatriz M. A., Nussenzweig, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712141/
https://www.ncbi.nlm.nih.gov/pubmed/26735921
http://dx.doi.org/10.1371/journal.ppat.1005370