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UIS2: A Unique Phosphatase Required for the Development of Plasmodium Liver Stages
Plasmodium salivary sporozoites are the infectious form of the malaria parasite and are dormant inside salivary glands of Anopheles mosquitoes. During dormancy, protein translation is inhibited by the kinase UIS1 that phosphorylates serine 59 in the eukaryotic initiation factor 2α (eIF2α). De-phosph...
Autores principales: | Zhang, Min, Mishra, Satish, Sakthivel, Ramanavelan, Fontoura, Beatriz M. A., Nussenzweig, Victor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712141/ https://www.ncbi.nlm.nih.gov/pubmed/26735921 http://dx.doi.org/10.1371/journal.ppat.1005370 |
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