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Erectile dysfunction in patients with liver disease related to chronic hepatitis B

BACKGROUND/AIMS: Despite sexual function making an important contribution to the quality of life, data on erectile function are relatively scant in patients with chronic liver disease. We evaluated the prevalence of and risk factors for erectile dysfunction (ED) in patients with liver disease relate...

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Autores principales: Kim, Min, Kim, Seul Young, Rou, Woo Sun, Hwang, Se Woong, Lee, Byung Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association for the Study of the Liver 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712162/
https://www.ncbi.nlm.nih.gov/pubmed/26770923
http://dx.doi.org/10.3350/cmh.2015.21.4.352
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author Kim, Min
Kim, Seul Young
Rou, Woo Sun
Hwang, Se Woong
Lee, Byung Seok
author_facet Kim, Min
Kim, Seul Young
Rou, Woo Sun
Hwang, Se Woong
Lee, Byung Seok
author_sort Kim, Min
collection PubMed
description BACKGROUND/AIMS: Despite sexual function making an important contribution to the quality of life, data on erectile function are relatively scant in patients with chronic liver disease. We evaluated the prevalence of and risk factors for erectile dysfunction (ED) in patients with liver disease related to hepatitis B, especially among those with chronic hepatitis B (CHB) or early-stage cirrhosis. METHODS: In total, 69 patients (35 with CHB and 34 with hepatitis-B-related liver cirrhosis [HBV-LC]) aged 40-59 years were analyzed. Child-Pugh classes of A and B were present in 30 (88.2%) and 4 (11.8%) of the patients with HBV-LC, respectively. The erectile function of the patients was evaluated using the Korean version of IIEF-5. RESULTS: The prevalence of any ED was 24.6% for all patients, and 8.6% and 41.2% for those with CHB and HBV-LC, respectively (P=0.002). While there was only one (2.9%) CHB patient for each stage of ED, mild, moderate, and severe ED stages were seen in three (8.8%), one (2.9%), and ten (29.4%) of the HBV-LC patients, respectively. Multiple regression analysis identified the type of liver disease (P=0.010), hypertension (P=0.022), score on the Beck Depression Inventory (P =0.044), and the serum albumin level (P=0.014) as significant independent factors for the presence of ED. CONCLUSIONS: The prevalence of ED was significantly higher in patients with early-stage HBV-LC than in those with CHB. Therefore, screening male patients with early viral cirrhosis for ED and providing appropriate support are needed, especially when the cirrhosis is accompanied by hypertension, depression, or a depressed level of serum albumin.
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spelling pubmed-47121622016-01-14 Erectile dysfunction in patients with liver disease related to chronic hepatitis B Kim, Min Kim, Seul Young Rou, Woo Sun Hwang, Se Woong Lee, Byung Seok Clin Mol Hepatol Original Article BACKGROUND/AIMS: Despite sexual function making an important contribution to the quality of life, data on erectile function are relatively scant in patients with chronic liver disease. We evaluated the prevalence of and risk factors for erectile dysfunction (ED) in patients with liver disease related to hepatitis B, especially among those with chronic hepatitis B (CHB) or early-stage cirrhosis. METHODS: In total, 69 patients (35 with CHB and 34 with hepatitis-B-related liver cirrhosis [HBV-LC]) aged 40-59 years were analyzed. Child-Pugh classes of A and B were present in 30 (88.2%) and 4 (11.8%) of the patients with HBV-LC, respectively. The erectile function of the patients was evaluated using the Korean version of IIEF-5. RESULTS: The prevalence of any ED was 24.6% for all patients, and 8.6% and 41.2% for those with CHB and HBV-LC, respectively (P=0.002). While there was only one (2.9%) CHB patient for each stage of ED, mild, moderate, and severe ED stages were seen in three (8.8%), one (2.9%), and ten (29.4%) of the HBV-LC patients, respectively. Multiple regression analysis identified the type of liver disease (P=0.010), hypertension (P=0.022), score on the Beck Depression Inventory (P =0.044), and the serum albumin level (P=0.014) as significant independent factors for the presence of ED. CONCLUSIONS: The prevalence of ED was significantly higher in patients with early-stage HBV-LC than in those with CHB. Therefore, screening male patients with early viral cirrhosis for ED and providing appropriate support are needed, especially when the cirrhosis is accompanied by hypertension, depression, or a depressed level of serum albumin. The Korean Association for the Study of the Liver 2015-12 2015-12-24 /pmc/articles/PMC4712162/ /pubmed/26770923 http://dx.doi.org/10.3350/cmh.2015.21.4.352 Text en Copyright © 2015 by The Korean Association for the Study of the Liver http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Kim, Min
Kim, Seul Young
Rou, Woo Sun
Hwang, Se Woong
Lee, Byung Seok
Erectile dysfunction in patients with liver disease related to chronic hepatitis B
title Erectile dysfunction in patients with liver disease related to chronic hepatitis B
title_full Erectile dysfunction in patients with liver disease related to chronic hepatitis B
title_fullStr Erectile dysfunction in patients with liver disease related to chronic hepatitis B
title_full_unstemmed Erectile dysfunction in patients with liver disease related to chronic hepatitis B
title_short Erectile dysfunction in patients with liver disease related to chronic hepatitis B
title_sort erectile dysfunction in patients with liver disease related to chronic hepatitis b
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712162/
https://www.ncbi.nlm.nih.gov/pubmed/26770923
http://dx.doi.org/10.3350/cmh.2015.21.4.352
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