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A Retrospective 10-Year, Single-Institution Study of Carotid Endarterectomy with a Focus on Elderly Patients

BACKGROUND AND PURPOSE: This study evaluated the outcome following surgery for carotid artery stenosis in a single institution during a 10-year period and the relevance of aging to access to surgery. METHODS: Between January 2001 and December 2010, 649 carotid endarterectomies (CEAs) were performed...

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Autores principales: Park, Hojong, Kwon, Tae-Won, Kwon, Sun U., Kang, Dong-Wha, Kim, Jong S., Chung, Young Soo, Shin, Sung, Han, Youngjin, Cho, Yong-Pil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Neurological Association 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712286/
https://www.ncbi.nlm.nih.gov/pubmed/26754779
http://dx.doi.org/10.3988/jcn.2016.12.1.49
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author Park, Hojong
Kwon, Tae-Won
Kwon, Sun U.
Kang, Dong-Wha
Kim, Jong S.
Chung, Young Soo
Shin, Sung
Han, Youngjin
Cho, Yong-Pil
author_facet Park, Hojong
Kwon, Tae-Won
Kwon, Sun U.
Kang, Dong-Wha
Kim, Jong S.
Chung, Young Soo
Shin, Sung
Han, Youngjin
Cho, Yong-Pil
author_sort Park, Hojong
collection PubMed
description BACKGROUND AND PURPOSE: This study evaluated the outcome following surgery for carotid artery stenosis in a single institution during a 10-year period and the relevance of aging to access to surgery. METHODS: Between January 2001 and December 2010, 649 carotid endarterectomies (CEAs) were performed in 596 patients for internal carotid artery occlusive disease at our institution; 596 patients received unilateral CEAs and 53 patients received bilateral CEAs. Data regarding patient characteristics, comorbidities, stroke, mortality, restenosis, and other surgical complications were obtained from a review of medical records. Since elderly and high-risk patients comprise a significant proportion of the patient group undergoing CEAs, differences in comorbidity and mortality were evaluated according to age when the patients were divided into three age groups: <70 years, 70-79 years, and ≥80 years. RESULTS: The mean age of the included patients was 67.5 years, and 88% were men. Symptomatic carotid stenosis was observed in 65.7% of patients. The rate of perioperative stroke and death (within 30 days of the procedure) was 1.84%. The overall mortality rate was higher among patients in the 70-79 years and >80 years age groups than among those in the <70 years age group, but there was no significant difference in stroke-related mortality among these three groups. CONCLUSIONS: CEA over a 10-year period has yielded acceptable outcomes in terms of stroke and mortality. Therefore, since CEA is a safe and effective strategy, it can be performed in elderly patients with acceptable life expectancy.
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spelling pubmed-47122862016-01-14 A Retrospective 10-Year, Single-Institution Study of Carotid Endarterectomy with a Focus on Elderly Patients Park, Hojong Kwon, Tae-Won Kwon, Sun U. Kang, Dong-Wha Kim, Jong S. Chung, Young Soo Shin, Sung Han, Youngjin Cho, Yong-Pil J Clin Neurol Original Article BACKGROUND AND PURPOSE: This study evaluated the outcome following surgery for carotid artery stenosis in a single institution during a 10-year period and the relevance of aging to access to surgery. METHODS: Between January 2001 and December 2010, 649 carotid endarterectomies (CEAs) were performed in 596 patients for internal carotid artery occlusive disease at our institution; 596 patients received unilateral CEAs and 53 patients received bilateral CEAs. Data regarding patient characteristics, comorbidities, stroke, mortality, restenosis, and other surgical complications were obtained from a review of medical records. Since elderly and high-risk patients comprise a significant proportion of the patient group undergoing CEAs, differences in comorbidity and mortality were evaluated according to age when the patients were divided into three age groups: <70 years, 70-79 years, and ≥80 years. RESULTS: The mean age of the included patients was 67.5 years, and 88% were men. Symptomatic carotid stenosis was observed in 65.7% of patients. The rate of perioperative stroke and death (within 30 days of the procedure) was 1.84%. The overall mortality rate was higher among patients in the 70-79 years and >80 years age groups than among those in the <70 years age group, but there was no significant difference in stroke-related mortality among these three groups. CONCLUSIONS: CEA over a 10-year period has yielded acceptable outcomes in terms of stroke and mortality. Therefore, since CEA is a safe and effective strategy, it can be performed in elderly patients with acceptable life expectancy. Korean Neurological Association 2016-01 2015-12-23 /pmc/articles/PMC4712286/ /pubmed/26754779 http://dx.doi.org/10.3988/jcn.2016.12.1.49 Text en Copyright © 2015 Korean Neurological Association http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Park, Hojong
Kwon, Tae-Won
Kwon, Sun U.
Kang, Dong-Wha
Kim, Jong S.
Chung, Young Soo
Shin, Sung
Han, Youngjin
Cho, Yong-Pil
A Retrospective 10-Year, Single-Institution Study of Carotid Endarterectomy with a Focus on Elderly Patients
title A Retrospective 10-Year, Single-Institution Study of Carotid Endarterectomy with a Focus on Elderly Patients
title_full A Retrospective 10-Year, Single-Institution Study of Carotid Endarterectomy with a Focus on Elderly Patients
title_fullStr A Retrospective 10-Year, Single-Institution Study of Carotid Endarterectomy with a Focus on Elderly Patients
title_full_unstemmed A Retrospective 10-Year, Single-Institution Study of Carotid Endarterectomy with a Focus on Elderly Patients
title_short A Retrospective 10-Year, Single-Institution Study of Carotid Endarterectomy with a Focus on Elderly Patients
title_sort retrospective 10-year, single-institution study of carotid endarterectomy with a focus on elderly patients
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712286/
https://www.ncbi.nlm.nih.gov/pubmed/26754779
http://dx.doi.org/10.3988/jcn.2016.12.1.49
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