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Prevalence of and risk factors for postprandial hypotension in older Chinese men

OBJECTIVE: To assess the prevalence of and risk factors for postprandial hypotension (PPH) among old and very old Chinese men. METHODS: The study included 349 Chinese men aged 65 and older, grouped into two age categories: group 1 (old) included 163 men aged 65 to 80 years; group 2 (very old) includ...

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Autores principales: Zou, Xiao, Cao, Jian, Li, Jian-Hua, Hu, Yi-Xin, Guo, Yu-Song, Si, Quan-Jin, Fan, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712364/
https://www.ncbi.nlm.nih.gov/pubmed/26788035
http://dx.doi.org/10.11909/j.issn.1671-5411.2015.06.003
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author Zou, Xiao
Cao, Jian
Li, Jian-Hua
Hu, Yi-Xin
Guo, Yu-Song
Si, Quan-Jin
Fan, Li
author_facet Zou, Xiao
Cao, Jian
Li, Jian-Hua
Hu, Yi-Xin
Guo, Yu-Song
Si, Quan-Jin
Fan, Li
author_sort Zou, Xiao
collection PubMed
description OBJECTIVE: To assess the prevalence of and risk factors for postprandial hypotension (PPH) among old and very old Chinese men. METHODS: The study included 349 Chinese men aged 65 and older, grouped into two age categories: group 1 (old) included 163 men aged 65 to 80 years; group 2 (very old) included 186 men aged over 80 years. Blood pressure changes after meals were assessed every 15 min by ambulatory blood pressure monitoring. Symptoms after meal ingestion and after standing up and changes in the baseline condition relative to blood pressure changes were observed continuously. Additional baseline data included body mass index, medical history, and medication use. RESULTS: The prevalence of PPH was 59.3% overall and was significantly higher in group 2 than group 1 (63.4% vs. 54.6%, P < 0.05). In group 2, the prevalence of PPH after breakfast (33.8%) and lunch (32.1%) were higher than that after supper (20.9%), P < 0.05. Hypertension and age were significant risk factors for PPH (OR = 2.188, 95% CI: 1.134−4.223, P = 0.02; OR = 1.86, 95% CI: 1.112−3.11, P = 0.018, respectively). In contrast, acarbose use was protective against PPH (OR = 0.4, 95% CI: 0.189−0.847, P = 0.017). The decrease in blood pressure during PPH was 20−40 mmHg and the maximum was 90 mmHg. PPH usually occurred at 30−60 min after a meal and lasted 30−120 min. CONCLUSIONS: These findings demonstrate that the prevalence of PPH in men aged over 80 years is significantly higher than those in men aged 65 to 80 years, and the blood pressure decline is also higher for men aged over 80 years. In addition, hypertension and age were main risk factors for PPH in the older men, which suggest that preventing and treating PPH is worthwhile.
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spelling pubmed-47123642016-01-19 Prevalence of and risk factors for postprandial hypotension in older Chinese men Zou, Xiao Cao, Jian Li, Jian-Hua Hu, Yi-Xin Guo, Yu-Song Si, Quan-Jin Fan, Li J Geriatr Cardiol Research Article OBJECTIVE: To assess the prevalence of and risk factors for postprandial hypotension (PPH) among old and very old Chinese men. METHODS: The study included 349 Chinese men aged 65 and older, grouped into two age categories: group 1 (old) included 163 men aged 65 to 80 years; group 2 (very old) included 186 men aged over 80 years. Blood pressure changes after meals were assessed every 15 min by ambulatory blood pressure monitoring. Symptoms after meal ingestion and after standing up and changes in the baseline condition relative to blood pressure changes were observed continuously. Additional baseline data included body mass index, medical history, and medication use. RESULTS: The prevalence of PPH was 59.3% overall and was significantly higher in group 2 than group 1 (63.4% vs. 54.6%, P < 0.05). In group 2, the prevalence of PPH after breakfast (33.8%) and lunch (32.1%) were higher than that after supper (20.9%), P < 0.05. Hypertension and age were significant risk factors for PPH (OR = 2.188, 95% CI: 1.134−4.223, P = 0.02; OR = 1.86, 95% CI: 1.112−3.11, P = 0.018, respectively). In contrast, acarbose use was protective against PPH (OR = 0.4, 95% CI: 0.189−0.847, P = 0.017). The decrease in blood pressure during PPH was 20−40 mmHg and the maximum was 90 mmHg. PPH usually occurred at 30−60 min after a meal and lasted 30−120 min. CONCLUSIONS: These findings demonstrate that the prevalence of PPH in men aged over 80 years is significantly higher than those in men aged 65 to 80 years, and the blood pressure decline is also higher for men aged over 80 years. In addition, hypertension and age were main risk factors for PPH in the older men, which suggest that preventing and treating PPH is worthwhile. Science Press 2015-11 /pmc/articles/PMC4712364/ /pubmed/26788035 http://dx.doi.org/10.11909/j.issn.1671-5411.2015.06.003 Text en Institute of Geriatric Cardiology http://creativecommons.org/licenses/by-nc-sa/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License, which allows readers to alter, transform, or build upon the article and then distribute the resulting work under the same or similar license to this one. The work must be attributed back to the original author and commercial use is not permitted without specific permission.
spellingShingle Research Article
Zou, Xiao
Cao, Jian
Li, Jian-Hua
Hu, Yi-Xin
Guo, Yu-Song
Si, Quan-Jin
Fan, Li
Prevalence of and risk factors for postprandial hypotension in older Chinese men
title Prevalence of and risk factors for postprandial hypotension in older Chinese men
title_full Prevalence of and risk factors for postprandial hypotension in older Chinese men
title_fullStr Prevalence of and risk factors for postprandial hypotension in older Chinese men
title_full_unstemmed Prevalence of and risk factors for postprandial hypotension in older Chinese men
title_short Prevalence of and risk factors for postprandial hypotension in older Chinese men
title_sort prevalence of and risk factors for postprandial hypotension in older chinese men
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712364/
https://www.ncbi.nlm.nih.gov/pubmed/26788035
http://dx.doi.org/10.11909/j.issn.1671-5411.2015.06.003
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