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Silvestrol induces early autophagy and apoptosis in human melanoma cells

BACKGROUND: Silvestrol is a cyclopenta[b]benzofuran that was isolated from the fruits and twigs of Aglaia foveolata, a plant indigenous to Borneo in Southeast Asia. The purpose of the current study was to determine if inhibition of protein synthesis caused by silvestrol triggers autophagy and apopto...

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Detalles Bibliográficos
Autores principales: Chen, Wei-Lun, Pan, Li, Kinghorn, A. Douglas, Swanson, Steven M., Burdette, Joanna E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712514/
https://www.ncbi.nlm.nih.gov/pubmed/26762417
http://dx.doi.org/10.1186/s12885-015-1988-0