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Deciphering the anti-angiogenic effect of endostatin/cyclophosphamide to normalize tumor micrangium through notch signaling pathway in colon cancer

BACKGROUND: The invasion of colon cancer is associated with the tumor angiogenesis. Endostatin is an important anti-angiogenic agent, and the additive effect of endostatin with a chemotherapeutic agent, cyclophosphamide, on micrangium has not been established. METHODS: Male BALB/c strain nude mice w...

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Detalles Bibliográficos
Autores principales: Lv, Jin-Yan, Hu, Tai-Yuan, Wang, Ruo-Yu, Zhu, Jin-Ming, Wang, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712526/
https://www.ncbi.nlm.nih.gov/pubmed/26762567
http://dx.doi.org/10.1186/s12957-015-0761-9

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