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Sequencing of lariat termini in S. cerevisiae reveals 5′ splice sites, branch points, and novel splicing events
Pre-mRNA splicing is a central step in the shaping of the eukaryotic transcriptome and in the regulation of gene expression. Yet, due to a focus on fully processed mRNA, common approaches for defining pre-mRNA splicing genome-wide are suboptimal—especially with respect to defining the branch point s...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712674/ https://www.ncbi.nlm.nih.gov/pubmed/26647463 http://dx.doi.org/10.1261/rna.052829.115 |