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Reduced levels of protein recoding by A-to-I RNA editing in Alzheimer's disease

Adenosine to inosine (A-to-I) RNA editing, catalyzed by the ADAR enzyme family, acts on dsRNA structures within pre-mRNA molecules. Editing of the coding part of the mRNA may lead to recoding, amino acid substitution in the resulting protein, possibly modifying its biochemical and biophysical proper...

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Detalles Bibliográficos
Autores principales:	Khermesh, Khen, D'Erchia, Anna Maria, Barak, Michal, Annese, Anita, Wachtel, Chaim, Levanon, Erez Y., Picardi, Ernesto, Eisenberg, Eli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712678/ https://www.ncbi.nlm.nih.gov/pubmed/26655226 http://dx.doi.org/10.1261/rna.054627.115

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