Reactivation of p53 by a Cytoskeletal Sensor to Control the Balance Between DNA Damage and Tumor Dissemination

BACKGROUND: Abnormal cell migration and invasion underlie metastasis, and actomyosin contractility is a key regulator of tumor invasion. The links between cancer migratory behavior and DNA damage are poorly understood. METHODS: Using 3D collagen systems to recapitulate melanoma extracellular matrix,...

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Detalles Bibliográficos
Autores principales: Herraiz, Cecilia, Calvo, Fernando, Pandya, Pahini, Cantelli, Gaia, Rodriguez-Hernandez, Irene, Orgaz, Jose L., Kang, NaRa, Chu, Tinghine, Sahai, Erik, Sanz-Moreno, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712681/
https://www.ncbi.nlm.nih.gov/pubmed/26464464
http://dx.doi.org/10.1093/jnci/djv289

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