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Plectin reinforces vascular integrity by mediating crosstalk between the vimentin and the actin networks

Mutations in the cytoskeletal linker protein plectin result in multisystemic diseases affecting skin and muscle with indications of additional vascular system involvement. To study the mechanisms underlying vascular disorders, we established plectin-deficient endothelial cell and mouse models. We sh...

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Detalles Bibliográficos
Autores principales: Osmanagic-Myers, Selma, Rus, Stefanie, Wolfram, Michael, Brunner, Daniela, Goldmann, Wolfgang H., Bonakdar, Navid, Fischer, Irmgard, Reipert, Siegfried, Zuzuarregui, Aurora, Walko, Gernot, Wiche, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712781/
https://www.ncbi.nlm.nih.gov/pubmed/26519478
http://dx.doi.org/10.1242/jcs.172056

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