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Plectin reinforces vascular integrity by mediating crosstalk between the vimentin and the actin networks
Mutations in the cytoskeletal linker protein plectin result in multisystemic diseases affecting skin and muscle with indications of additional vascular system involvement. To study the mechanisms underlying vascular disorders, we established plectin-deficient endothelial cell and mouse models. We sh...
Autores principales: | Osmanagic-Myers, Selma, Rus, Stefanie, Wolfram, Michael, Brunner, Daniela, Goldmann, Wolfgang H., Bonakdar, Navid, Fischer, Irmgard, Reipert, Siegfried, Zuzuarregui, Aurora, Walko, Gernot, Wiche, Gerhard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712781/ https://www.ncbi.nlm.nih.gov/pubmed/26519478 http://dx.doi.org/10.1242/jcs.172056 |
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