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A Shh-Foxf-Fgf18-Shh Molecular Circuit Regulating Palate Development

Cleft palate is among the most common birth defects in humans. Previous studies have shown that Shh signaling plays critical roles in palate development and regulates expression of several members of the forkhead-box (Fox) family transcription factors, including Foxf1 and Foxf2, in the facial primor...

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Detalles Bibliográficos
Autores principales: Xu, Jingyue, Liu, Han, Lan, Yu, Aronow, Bruce J., Kalinichenko, Vladimir V., Jiang, Rulang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712829/
https://www.ncbi.nlm.nih.gov/pubmed/26745863
http://dx.doi.org/10.1371/journal.pgen.1005769