Human stem cells from single blastomeres reveal pathways of embryonic or trophoblast fate specification

Mechanisms of initial cell fate decisions differ among species. To gain insights into lineage allocation in humans, we derived ten human embryonic stem cell lines (designated UCSFB1-10) from single blastomeres of four 8-cell embryos and one 12-cell embryo from a single couple. Compared with numerous...

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Detalles Bibliográficos
Autores principales: Zdravkovic, Tamara, Nazor, Kristopher L., Larocque, Nicholas, Gormley, Matthew, Donne, Matthew, Hunkapillar, Nathan, Giritharan, Gnanaratnam, Bernstein, Harold S., Wei, Grace, Hebrok, Matthias, Zeng, Xianmin, Genbacev, Olga, Mattis, Aras, McMaster, Michael T., Krtolica, Ana, Valbuena, Diana, Simón, Carlos, Laurent, Louise C., Loring, Jeanne F., Fisher, Susan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Stem Cells and Regeneration
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712832/
https://www.ncbi.nlm.nih.gov/pubmed/26483210
http://dx.doi.org/10.1242/dev.122846

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712832/
https://www.ncbi.nlm.nih.gov/pubmed/26483210
http://dx.doi.org/10.1242/dev.122846

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