Cargando…

Comparison of Irradiation and Wolbachia Based Approaches for Sterile-Male Strategies Targeting Aedes albopictus

The global expansion of Aedes albopictus together with the absence of vaccines for most of the arboviruses transmitted by this mosquito has stimulated the development of sterile-male strategies aiming at controlling disease transmission through the suppression of natural vector populations. In this...

Descripción completa

Detalles Bibliográficos
Autores principales: Atyame, Célestine M., Labbé, Pierrick, Lebon, Cyrille, Weill, Mylène, Moretti, Riccardo, Marini, Francesca, Gouagna, Louis Clément, Calvitti, Maurizio, Tortosa, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713058/
https://www.ncbi.nlm.nih.gov/pubmed/26765951
http://dx.doi.org/10.1371/journal.pone.0146834
_version_ 1782410135279239168
author Atyame, Célestine M.
Labbé, Pierrick
Lebon, Cyrille
Weill, Mylène
Moretti, Riccardo
Marini, Francesca
Gouagna, Louis Clément
Calvitti, Maurizio
Tortosa, Pablo
author_facet Atyame, Célestine M.
Labbé, Pierrick
Lebon, Cyrille
Weill, Mylène
Moretti, Riccardo
Marini, Francesca
Gouagna, Louis Clément
Calvitti, Maurizio
Tortosa, Pablo
author_sort Atyame, Célestine M.
collection PubMed
description The global expansion of Aedes albopictus together with the absence of vaccines for most of the arboviruses transmitted by this mosquito has stimulated the development of sterile-male strategies aiming at controlling disease transmission through the suppression of natural vector populations. In this context, two environmentally friendly control strategies, namely the Sterile Insect Technique (SIT) and the Wolbachia-based Incompatible Insect Technique (IIT) are currently being developed in several laboratories worldwide. So far however, there is a lack of comparative assessment of these strategies under the same controlled conditions. Here, we compared the mating capacities, i.e. insemination capacity, sterilization capacity and mating competitiveness of irradiated (35 Gy) and incompatible Ae. albopictus males at different ages and ratios under laboratory controlled conditions. Our data show that there was no significant difference in insemination capacity of irradiated and incompatible males, both male types showing lower capacities than untreated males at 1 day but recovering full capacity within 5 days following emergence. Regarding mating competitiveness trials, a global observed trend is that incompatible males tend to induce a lower hatching rate than irradiated males in cage controlled confrontations. More specifically, incompatible males were found more competitive than irradiated males in 5:1 ratio regardless of age, while irradiated males were only found more competitive than incompatible males in the 1:1 ratio at 10 days old. Overall, under the tested conditions, IIT seemed to be slightly more effective than SIT. However, considering that a single strategy will likely not be adapted to all environments, our data stimulates the need for comparative assessments of distinct strategies in up-scaled conditions in order to identify the most suitable and safe sterilizing technology to be implemented in a specific environmental setting and to identify the parameters requiring fine tuning in order to reach optimal release conditions.
format Online
Article
Text
id pubmed-4713058
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-47130582016-01-26 Comparison of Irradiation and Wolbachia Based Approaches for Sterile-Male Strategies Targeting Aedes albopictus Atyame, Célestine M. Labbé, Pierrick Lebon, Cyrille Weill, Mylène Moretti, Riccardo Marini, Francesca Gouagna, Louis Clément Calvitti, Maurizio Tortosa, Pablo PLoS One Research Article The global expansion of Aedes albopictus together with the absence of vaccines for most of the arboviruses transmitted by this mosquito has stimulated the development of sterile-male strategies aiming at controlling disease transmission through the suppression of natural vector populations. In this context, two environmentally friendly control strategies, namely the Sterile Insect Technique (SIT) and the Wolbachia-based Incompatible Insect Technique (IIT) are currently being developed in several laboratories worldwide. So far however, there is a lack of comparative assessment of these strategies under the same controlled conditions. Here, we compared the mating capacities, i.e. insemination capacity, sterilization capacity and mating competitiveness of irradiated (35 Gy) and incompatible Ae. albopictus males at different ages and ratios under laboratory controlled conditions. Our data show that there was no significant difference in insemination capacity of irradiated and incompatible males, both male types showing lower capacities than untreated males at 1 day but recovering full capacity within 5 days following emergence. Regarding mating competitiveness trials, a global observed trend is that incompatible males tend to induce a lower hatching rate than irradiated males in cage controlled confrontations. More specifically, incompatible males were found more competitive than irradiated males in 5:1 ratio regardless of age, while irradiated males were only found more competitive than incompatible males in the 1:1 ratio at 10 days old. Overall, under the tested conditions, IIT seemed to be slightly more effective than SIT. However, considering that a single strategy will likely not be adapted to all environments, our data stimulates the need for comparative assessments of distinct strategies in up-scaled conditions in order to identify the most suitable and safe sterilizing technology to be implemented in a specific environmental setting and to identify the parameters requiring fine tuning in order to reach optimal release conditions. Public Library of Science 2016-01-14 /pmc/articles/PMC4713058/ /pubmed/26765951 http://dx.doi.org/10.1371/journal.pone.0146834 Text en © 2016 Atyame et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Atyame, Célestine M.
Labbé, Pierrick
Lebon, Cyrille
Weill, Mylène
Moretti, Riccardo
Marini, Francesca
Gouagna, Louis Clément
Calvitti, Maurizio
Tortosa, Pablo
Comparison of Irradiation and Wolbachia Based Approaches for Sterile-Male Strategies Targeting Aedes albopictus
title Comparison of Irradiation and Wolbachia Based Approaches for Sterile-Male Strategies Targeting Aedes albopictus
title_full Comparison of Irradiation and Wolbachia Based Approaches for Sterile-Male Strategies Targeting Aedes albopictus
title_fullStr Comparison of Irradiation and Wolbachia Based Approaches for Sterile-Male Strategies Targeting Aedes albopictus
title_full_unstemmed Comparison of Irradiation and Wolbachia Based Approaches for Sterile-Male Strategies Targeting Aedes albopictus
title_short Comparison of Irradiation and Wolbachia Based Approaches for Sterile-Male Strategies Targeting Aedes albopictus
title_sort comparison of irradiation and wolbachia based approaches for sterile-male strategies targeting aedes albopictus
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713058/
https://www.ncbi.nlm.nih.gov/pubmed/26765951
http://dx.doi.org/10.1371/journal.pone.0146834
work_keys_str_mv AT atyamecelestinem comparisonofirradiationandwolbachiabasedapproachesforsterilemalestrategiestargetingaedesalbopictus
AT labbepierrick comparisonofirradiationandwolbachiabasedapproachesforsterilemalestrategiestargetingaedesalbopictus
AT leboncyrille comparisonofirradiationandwolbachiabasedapproachesforsterilemalestrategiestargetingaedesalbopictus
AT weillmylene comparisonofirradiationandwolbachiabasedapproachesforsterilemalestrategiestargetingaedesalbopictus
AT morettiriccardo comparisonofirradiationandwolbachiabasedapproachesforsterilemalestrategiestargetingaedesalbopictus
AT marinifrancesca comparisonofirradiationandwolbachiabasedapproachesforsterilemalestrategiestargetingaedesalbopictus
AT gouagnalouisclement comparisonofirradiationandwolbachiabasedapproachesforsterilemalestrategiestargetingaedesalbopictus
AT calvittimaurizio comparisonofirradiationandwolbachiabasedapproachesforsterilemalestrategiestargetingaedesalbopictus
AT tortosapablo comparisonofirradiationandwolbachiabasedapproachesforsterilemalestrategiestargetingaedesalbopictus