Developmentally regulated GTP-binding protein 2 coordinates Rab5 activity and transferrin recycling

The small GTPase Rab5 regulates the early endocytic pathway of transferrin (Tfn), and Rab5 deactivation is required for Tfn recycling. Rab5 deactivation is achieved by RabGAP5, a GTPase-activating protein, on the endosomes. Here we report that recruitment of RabGAP5 is insufficient to deactivate Rab...

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Detalles Bibliográficos
Autores principales: Mani, Muralidharan, Lee, Unn Hwa, Yoon, Nal Ae, Kim, Hyo Jeong, Ko, Myoung Seok, Seol, Wongi, Joe, Yeonsoo, Chung, Hun Taeg, Lee, Byung Ju, Moon, Chang Hoon, Cho, Wha Ja, Park, Jeong Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713135/
https://www.ncbi.nlm.nih.gov/pubmed/26582392
http://dx.doi.org/10.1091/mbc.E15-08-0558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713135/
https://www.ncbi.nlm.nih.gov/pubmed/26582392
http://dx.doi.org/10.1091/mbc.E15-08-0558

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